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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG4
All Species:
28.48
Human Site:
T22
Identified Species:
44.76
UniProt:
P49917
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49917
NP_001091738.1
911
103971
T22
P
F
A
D
L
C
S
T
L
E
R
I
Q
K
S
Chimpanzee
Pan troglodytes
XP_509726
911
103942
T22
P
F
A
D
L
C
S
T
L
E
R
I
Q
K
S
Rhesus Macaque
Macaca mulatta
XP_001084107
642
73046
Dog
Lupus familis
XP_542663
911
104163
T22
P
F
A
D
L
C
S
T
L
E
R
I
Q
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTF7
911
104067
T22
P
F
A
D
L
C
S
T
L
E
R
I
Q
K
G
Rat
Rattus norvegicus
NP_001099565
911
104477
T22
P
F
A
D
L
C
S
T
L
E
R
I
Q
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YB1
912
104431
T27
P
F
A
D
L
C
S
T
L
E
R
I
Q
T
C
Frog
Xenopus laevis
NP_001081114
911
104084
T27
P
F
A
D
L
C
C
T
L
E
K
I
Q
K
C
Zebra Danio
Brachydanio rerio
NP_001096593
909
103624
V27
P
F
I
H
L
C
T
V
L
E
K
I
Q
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572907
918
104813
T24
L
F
E
K
I
K
A
T
Q
K
V
A
N
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188102
952
108709
F60
P
F
V
Q
L
C
G
F
L
E
R
V
Q
K
K
Poplar Tree
Populus trichocarpa
XP_002325262
1242
139306
F22
F
S
I
L
V
S
L
F
N
W
I
S
K
T
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LL84
1219
137833
T22
N
W
I
Q
K
S
K
T
S
S
Q
K
R
S
K
Baker's Yeast
Sacchar. cerevisiae
Q08387
944
108496
W22
A
P
S
P
D
F
K
W
L
C
E
E
L
F
V
Red Bread Mold
Neurospora crassa
Q7SB49
1046
118891
L29
Y
G
A
G
T
L
S
L
E
E
L
D
E
Q
P
Conservation
Percent
Protein Identity:
100
99.4
68.9
91
N.A.
86.9
86.1
N.A.
N.A.
76.5
72.5
64.1
N.A.
29.7
N.A.
N.A.
48.5
Protein Similarity:
100
99.7
69.8
95.5
N.A.
92.5
92
N.A.
N.A.
87.1
84
79.3
N.A.
51.3
N.A.
N.A.
65.4
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
60
N.A.
20
N.A.
N.A.
60
P-Site Similarity:
100
100
0
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
80
N.A.
40
N.A.
N.A.
66.6
Percent
Protein Identity:
27.2
N.A.
N.A.
27.6
25.5
29.2
Protein Similarity:
43.3
N.A.
N.A.
44.9
46.9
47.2
P-Site Identity:
0
N.A.
N.A.
6.6
6.6
20
P-Site Similarity:
13.3
N.A.
N.A.
26.6
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
54
0
0
0
7
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
60
7
0
0
7
0
0
0
0
14
% C
% Asp:
0
0
0
47
7
0
0
0
0
0
0
7
0
0
0
% D
% Glu:
0
0
7
0
0
0
0
0
7
67
7
7
7
0
7
% E
% Phe:
7
67
0
0
0
7
0
14
0
0
0
0
0
7
0
% F
% Gly:
0
7
0
7
0
0
7
0
0
0
0
0
0
0
14
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
20
0
7
0
0
0
0
0
7
54
0
0
0
% I
% Lys:
0
0
0
7
7
7
14
0
0
7
14
7
7
54
20
% K
% Leu:
7
0
0
7
60
7
7
7
67
0
7
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% N
% Pro:
60
7
0
7
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
14
0
0
0
0
7
0
7
0
60
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
47
0
7
7
0
% R
% Ser:
0
7
7
0
0
14
47
0
7
7
0
7
0
7
20
% S
% Thr:
0
0
0
0
7
0
7
60
0
0
0
0
0
14
7
% T
% Val:
0
0
7
0
7
0
0
7
0
0
7
7
0
0
7
% V
% Trp:
0
7
0
0
0
0
0
7
0
7
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _