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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG4
All Species:
28.18
Human Site:
Y386
Identified Species:
44.29
UniProt:
P49917
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49917
NP_001091738.1
911
103971
Y386
H
E
T
L
R
K
R
Y
E
I
L
S
S
I
F
Chimpanzee
Pan troglodytes
XP_509726
911
103942
Y386
H
E
T
L
R
K
R
Y
E
I
L
S
S
I
F
Rhesus Macaque
Macaca mulatta
XP_001084107
642
73046
K162
V
A
S
N
N
S
A
K
R
K
D
L
I
K
K
Dog
Lupus familis
XP_542663
911
104163
Y386
R
E
T
L
K
K
R
Y
E
I
L
T
S
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTF7
911
104067
Y386
R
E
T
L
R
K
R
Y
E
I
L
S
S
T
F
Rat
Rattus norvegicus
NP_001099565
911
104477
Y386
R
E
T
L
R
K
R
Y
D
I
L
S
S
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YB1
912
104431
Y391
H
E
S
L
S
K
R
Y
K
I
L
S
N
V
F
Frog
Xenopus laevis
NP_001081114
911
104084
Y391
H
E
T
L
R
K
R
Y
D
I
L
K
E
I
F
Zebra Danio
Brachydanio rerio
NP_001096593
909
103624
Y391
K
E
P
L
K
K
R
Y
E
S
L
E
T
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572907
918
104813
A395
D
H
T
Y
I
Q
R
A
Y
K
L
Q
K
L
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188102
952
108709
L423
N
R
P
L
K
E
R
L
N
Y
L
P
K
V
F
Poplar Tree
Populus trichocarpa
XP_002325262
1242
139306
H369
H
Q
T
L
K
E
R
H
E
L
L
R
K
V
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LL84
1219
137833
H361
H
Q
S
L
K
E
R
H
E
L
L
K
K
V
V
Baker's Yeast
Sacchar. cerevisiae
Q08387
944
108496
K401
P
L
P
L
H
Q
R
K
Q
Y
L
N
S
I
L
Red Bread Mold
Neurospora crassa
Q7SB49
1046
118891
R453
E
Y
T
L
N
D
R
R
R
A
L
E
R
A
V
Conservation
Percent
Protein Identity:
100
99.4
68.9
91
N.A.
86.9
86.1
N.A.
N.A.
76.5
72.5
64.1
N.A.
29.7
N.A.
N.A.
48.5
Protein Similarity:
100
99.7
69.8
95.5
N.A.
92.5
92
N.A.
N.A.
87.1
84
79.3
N.A.
51.3
N.A.
N.A.
65.4
P-Site Identity:
100
100
0
73.3
N.A.
86.6
80
N.A.
N.A.
66.6
80
53.3
N.A.
20
N.A.
N.A.
26.6
P-Site Similarity:
100
100
6.6
93.3
N.A.
86.6
86.6
N.A.
N.A.
93.3
86.6
73.3
N.A.
33.3
N.A.
N.A.
53.3
Percent
Protein Identity:
27.2
N.A.
N.A.
27.6
25.5
29.2
Protein Similarity:
43.3
N.A.
N.A.
44.9
46.9
47.2
P-Site Identity:
40
N.A.
N.A.
33.3
33.3
26.6
P-Site Similarity:
80
N.A.
N.A.
80
53.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
7
7
0
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
7
0
0
14
0
7
0
0
0
0
% D
% Glu:
7
54
0
0
0
20
0
0
47
0
0
14
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
40
7
0
0
7
0
0
14
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
47
0
0
7
27
7
% I
% Lys:
7
0
0
0
34
54
0
14
7
14
0
14
27
7
7
% K
% Leu:
0
7
0
87
0
0
0
7
0
14
94
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
14
0
0
0
7
0
0
7
7
0
0
% N
% Pro:
7
0
20
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
14
0
0
0
14
0
0
7
0
0
7
0
0
0
% Q
% Arg:
20
7
0
0
34
0
94
7
14
0
0
7
7
0
0
% R
% Ser:
0
0
20
0
7
7
0
0
0
7
0
34
40
0
0
% S
% Thr:
0
0
60
0
0
0
0
0
0
0
0
7
7
14
0
% T
% Val:
7
0
0
0
0
0
0
0
0
0
0
0
0
40
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
0
0
54
7
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _