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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRE11A
All Species:
37.27
Human Site:
T36
Identified Species:
58.57
UniProt:
P49959
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49959
NP_005581.2
708
80593
T36
D
A
V
R
G
N
D
T
F
V
T
L
D
E
I
Chimpanzee
Pan troglodytes
XP_001142343
708
80653
T36
D
P
V
R
G
N
D
T
F
V
T
L
D
E
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542244
708
80700
T36
D
A
V
R
G
N
D
T
Y
V
T
L
D
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61216
706
80204
T36
D
A
V
R
G
N
D
T
F
V
T
F
D
E
I
Rat
Rattus norvegicus
Q9JIM0
706
80103
T36
D
A
V
R
G
N
D
T
F
V
T
F
D
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513434
706
80323
T36
D
A
V
R
G
N
D
T
F
A
T
L
D
E
I
Chicken
Gallus gallus
Q9IAM7
700
80005
T36
D
A
V
R
G
N
D
T
F
V
T
F
N
E
I
Frog
Xenopus laevis
Q9W6K1
711
81112
S37
D
A
V
R
G
N
D
S
F
V
A
F
D
E
I
Zebra Danio
Brachydanio rerio
NP_001001407
619
70401
T37
D
A
I
R
G
N
D
T
F
V
T
F
D
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523547
620
69267
S38
D
A
V
R
G
E
D
S
F
T
A
F
E
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23255
728
81540
A89
K
A
N
I
H
M
D
A
V
N
T
F
E
E
V
Sea Urchin
Strong. purpuratus
XP_798167
515
58684
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XGM2
720
80272
E39
D
S
F
K
A
F
E
E
I
C
S
I
A
E
E
Baker's Yeast
Sacchar. cerevisiae
P32829
692
77632
E38
D
S
W
K
T
F
H
E
V
M
M
L
A
K
N
Red Bread Mold
Neurospora crassa
Q9C291
739
83526
E38
D
S
W
R
T
F
D
E
I
M
Q
I
A
K
K
Conservation
Percent
Protein Identity:
100
99.4
N.A.
93.7
N.A.
88.2
88.4
N.A.
85
73.5
72.8
61.2
N.A.
39.5
N.A.
32.6
42.6
Protein Similarity:
100
99.4
N.A.
97.1
N.A.
93.7
93.7
N.A.
92.3
85.5
85
75.2
N.A.
55.6
N.A.
50.6
56.9
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
80
86.6
N.A.
60
N.A.
26.6
0
P-Site Similarity:
100
93.3
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
93.3
N.A.
73.3
N.A.
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.1
35.3
33.8
Protein Similarity:
N.A.
N.A.
N.A.
57.9
53.3
52.5
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
0
0
7
0
0
7
0
7
14
0
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
87
0
0
0
0
0
80
0
0
0
0
0
54
0
0
% D
% Glu:
0
0
0
0
0
7
7
20
0
0
0
0
14
80
7
% E
% Phe:
0
0
7
0
0
20
0
0
60
0
0
47
0
0
0
% F
% Gly:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
7
0
0
0
0
14
0
0
14
0
0
67
% I
% Lys:
7
0
0
14
0
0
0
0
0
0
0
0
0
14
7
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
14
7
0
0
0
0
% M
% Asn:
0
0
7
0
0
60
0
0
0
7
0
0
7
0
7
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
74
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
0
0
0
0
0
14
0
0
7
0
0
0
0
% S
% Thr:
0
0
0
0
14
0
0
54
0
7
60
0
0
0
0
% T
% Val:
0
0
60
0
0
0
0
0
14
54
0
0
0
0
7
% V
% Trp:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _