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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KHK
All Species:
28.18
Human Site:
S242
Identified Species:
77.5
UniProt:
P50053
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50053
NP_000212.1
298
32730
S242
P
D
G
K
L
L
H
S
D
A
F
P
P
P
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089839
303
33195
S242
P
D
G
K
L
I
H
S
D
A
F
P
P
P
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97328
298
32732
S242
P
D
G
Q
L
L
H
S
D
A
F
P
P
P
R
Rat
Rattus norvegicus
Q02974
298
32731
S242
P
D
G
Q
L
L
H
S
D
A
F
P
P
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509966
320
34497
S242
P
D
G
Q
L
L
H
S
D
A
F
P
P
P
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087493
298
32564
S242
P
D
G
S
V
V
H
S
G
A
F
S
P
E
N
Zebra Danio
Brachydanio rerio
NP_001002636
299
32608
S242
P
D
G
V
I
I
H
S
D
A
F
P
P
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649181
306
34100
M243
A
N
G
N
Y
Y
E
M
S
S
Y
K
Q
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792986
312
34376
S250
E
S
G
R
I
V
H
S
P
T
Y
P
P
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97
N.A.
N.A.
80.1
79.5
N.A.
70
N.A.
67.4
64.2
N.A.
34.3
N.A.
N.A.
43.2
Protein Similarity:
100
N.A.
97.6
N.A.
N.A.
89.9
90.2
N.A.
80.3
N.A.
83.2
82.6
N.A.
54.2
N.A.
N.A.
64.4
P-Site Identity:
100
N.A.
93.3
N.A.
N.A.
93.3
93.3
N.A.
93.3
N.A.
53.3
66.6
N.A.
6.6
N.A.
N.A.
33.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
100
N.A.
66.6
86.6
N.A.
33.3
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
78
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
78
0
0
0
0
0
0
67
0
0
0
0
12
0
% D
% Glu:
12
0
0
0
0
0
12
0
0
0
0
0
0
23
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
78
0
0
0
0
% F
% Gly:
0
0
100
0
0
0
0
0
12
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
89
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
23
23
0
0
0
0
0
0
0
12
0
% I
% Lys:
0
0
0
23
0
0
0
0
0
0
0
12
0
0
23
% K
% Leu:
0
0
0
0
56
45
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
12
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
78
0
0
0
0
0
0
0
12
0
0
78
89
56
0
% P
% Gln:
0
0
0
34
0
0
0
0
0
0
0
0
12
0
12
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
56
% R
% Ser:
0
12
0
12
0
0
0
89
12
12
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% T
% Val:
0
0
0
12
12
23
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
12
0
0
0
0
23
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _