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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNG4 All Species: 32.12
Human Site: S12 Identified Species: 64.24
UniProt: P50150 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50150 NP_001092191.1 75 8389 S12 M S N N S T T S I S Q A R K A
Chimpanzee Pan troglodytes XP_522854 102 11214 S39 M A S N N T A S I A Q A R K L
Rhesus Macaque Macaca mulatta XP_001110597 151 16826 S88 M S N N S T T S I S Q A R K A
Dog Lupus familis XP_849303 105 11945 S42 M S N N S T T S I S Q A R K A
Cat Felis silvestris
Mouse Mus musculus P50153 75 8386 S12 M S N N S T T S I S Q A R K A
Rat Rattus norvegicus P63077 70 7825 R12 M A K I A E A R K T V E Q L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515398 125 13844 S62 M A S N N T A S I A Q A R K L
Chicken Gallus gallus XP_001233858 74 8268 I12 T S N S T T N I S Q A R K A V
Frog Xenopus laevis NP_001086762 75 8370 S12 M S N N S T T S I S Q A R K A
Zebra Danio Brachydanio rerio XP_001335976 75 8328 S12 M A N N S T A S I S Q A R K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P38040 70 8112 R12 S S S L Q Q Q R V V V E Q L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54406 62 6995 T8 M E N I K A S T E Q L C A E A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.8 49.6 71.4 N.A. 98.6 58.6 N.A. 48 84 89.3 88 N.A. 41.3 N.A. 37.3 N.A.
Protein Similarity: 100 67.6 49.6 71.4 N.A. 100 78.6 N.A. 54.4 94.6 97.3 98.6 N.A. 57.3 N.A. 53.3 N.A.
P-Site Identity: 100 60 100 100 N.A. 100 6.6 N.A. 60 20 100 86.6 N.A. 6.6 N.A. 20 N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 100 33.3 N.A. 86.6 40 100 93.3 N.A. 26.6 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 0 0 9 9 34 0 0 17 9 67 9 9 59 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 0 0 9 0 0 9 0 0 17 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 17 0 0 0 9 67 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 9 0 0 0 9 0 0 0 9 67 9 % K
% Leu: 0 0 0 9 0 0 0 0 0 0 9 0 0 17 17 % L
% Met: 84 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 67 67 17 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 9 9 0 0 17 67 0 17 0 0 % Q
% Arg: 0 0 0 0 0 0 0 17 0 0 0 9 67 0 9 % R
% Ser: 9 59 25 9 50 0 9 67 9 50 0 0 0 0 0 % S
% Thr: 9 0 0 0 9 75 42 9 0 9 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 9 9 17 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _