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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDH3A
All Species:
20.3
Human Site:
S11
Identified Species:
29.78
UniProt:
P50213
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50213
NP_005521.1
366
39592
S11
P
A
W
I
S
K
V
S
R
L
L
G
A
F
H
Chimpanzee
Pan troglodytes
XP_510524
341
36949
Rhesus Macaque
Macaca mulatta
XP_001106839
288
31390
Dog
Lupus familis
XP_536213
366
39739
S11
P
A
W
I
S
K
V
S
R
L
L
G
A
F
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6R2
366
39620
S11
S
A
W
V
S
K
V
S
R
L
L
G
A
F
H
Rat
Rattus norvegicus
Q99NA5
366
39595
S11
S
A
W
V
S
K
V
S
R
L
L
G
A
F
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513325
359
38883
S11
S
R
L
L
G
A
F
S
N
S
K
Q
V
T
R
Chicken
Gallus gallus
XP_413748
397
43524
P34
P
A
R
G
R
Q
C
P
Q
P
R
L
G
R
N
Frog
Xenopus laevis
NP_001085990
368
40203
S13
S
A
W
R
S
L
I
S
R
V
A
G
A
I
T
Zebra Danio
Brachydanio rerio
NP_957245
365
39965
M13
R
S
A
V
S
C
I
M
G
A
I
K
T
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWH4
377
40826
T27
D
A
P
A
V
T
A
T
P
A
V
S
Q
V
N
Honey Bee
Apis mellifera
XP_392811
358
39117
P11
Q
W
I
R
N
A
V
P
K
I
G
C
V
R
F
Nematode Worm
Caenorhab. elegans
Q93714
358
38448
S11
K
C
I
K
K
A
S
S
T
V
G
Q
S
I
R
Sea Urchin
Strong. purpuratus
XP_792505
368
39889
T11
K
V
W
T
S
L
K
T
G
V
S
R
S
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q945K7
374
40606
V23
S
T
Q
I
L
G
A
V
N
S
S
S
G
A
A
Baker's Yeast
Sacchar. cerevisiae
P28241
369
39721
A16
N
T
S
R
R
F
L
A
T
V
K
Q
P
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
78.4
97.5
N.A.
97.5
97.2
N.A.
93.7
81.8
85
84.9
N.A.
67.6
68.3
68.3
69.8
Protein Similarity:
100
92.9
78.6
98.6
N.A.
98.6
98.6
N.A.
95
85.6
90.7
91.8
N.A.
79.8
80.5
77
80.4
P-Site Identity:
100
0
0
100
N.A.
86.6
86.6
N.A.
6.6
13.3
46.6
6.6
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
0
0
100
N.A.
93.3
93.3
N.A.
13.3
33.3
60
33.3
N.A.
26.6
26.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
54
52
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.9
66.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
44
7
7
0
19
13
7
0
13
7
0
32
7
7
% A
% Cys:
0
7
0
0
0
7
7
0
0
0
0
7
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
7
0
0
0
0
0
0
25
7
% F
% Gly:
0
0
0
7
7
7
0
0
13
0
13
32
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% H
% Ile:
0
0
13
19
0
0
13
0
0
7
7
0
0
13
7
% I
% Lys:
13
0
0
7
7
25
7
0
7
0
13
7
0
0
0
% K
% Leu:
0
0
7
7
7
13
7
0
0
25
25
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
0
0
0
13
0
0
0
0
0
19
% N
% Pro:
19
0
7
0
0
0
0
13
7
7
0
0
7
0
0
% P
% Gln:
7
0
7
0
0
7
0
0
7
0
0
19
7
7
0
% Q
% Arg:
7
7
7
19
13
0
0
0
32
0
7
7
0
13
13
% R
% Ser:
32
7
7
0
44
0
7
44
0
13
13
13
13
7
0
% S
% Thr:
0
13
0
7
0
7
0
13
13
0
0
0
7
7
13
% T
% Val:
0
7
0
19
7
0
32
7
0
25
7
0
13
7
0
% V
% Trp:
0
7
38
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _