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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEOX2
All Species:
18.18
Human Site:
S174
Identified Species:
50
UniProt:
P50222
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50222
NP_005915.2
304
33594
S174
R
K
S
D
S
S
D
S
Q
E
G
N
Y
K
S
Chimpanzee
Pan troglodytes
A2T779
254
27861
R150
X
X
E
K
K
S
S
R
R
R
K
E
S
S
D
Rhesus Macaque
Macaca mulatta
XP_001113649
254
28055
R150
E
T
E
K
K
S
S
R
R
R
K
E
S
S
D
Dog
Lupus familis
XP_539446
303
33438
S173
R
K
S
D
S
S
D
S
Q
E
G
N
Y
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P32443
303
33487
S173
R
K
S
D
S
S
D
S
Q
E
G
N
Y
K
S
Rat
Rattus norvegicus
P39020
303
33587
S173
R
K
S
D
S
S
D
S
Q
E
G
N
Y
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511619
184
20895
K80
A
F
T
K
E
Q
I
K
E
L
E
A
E
F
A
Chicken
Gallus gallus
Frog
Xenopus laevis
P39021
298
33227
S168
R
K
S
D
S
S
D
S
Q
E
G
S
Y
K
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192397
342
36509
E183
S
N
G
N
V
P
G
E
Q
G
G
Y
K
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.4
39.1
99.3
N.A.
97.6
97.3
N.A.
49.3
N.A.
83.8
N.A.
N.A.
N.A.
N.A.
N.A.
30.7
Protein Similarity:
100
48.3
49
99.6
N.A.
98.6
98.3
N.A.
56.9
N.A.
91.1
N.A.
N.A.
N.A.
N.A.
N.A.
43.2
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
0
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
100
N.A.
20
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
56
0
0
56
0
0
0
0
0
0
0
23
% D
% Glu:
12
0
23
0
12
0
0
12
12
56
12
23
12
0
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
12
0
0
0
12
0
0
12
67
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
56
0
34
23
0
0
12
0
0
23
0
12
56
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
12
0
0
0
0
0
0
0
45
0
0
0
% N
% Pro:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
67
0
0
0
0
12
0
% Q
% Arg:
56
0
0
0
0
0
0
23
23
23
0
0
0
0
0
% R
% Ser:
12
0
56
0
56
78
23
56
0
0
0
12
23
23
56
% S
% Thr:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
56
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _