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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPYR1
All Species:
11.82
Human Site:
Y238
Identified Species:
23.64
UniProt:
P50391
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50391
NP_005963.3
375
42195
Y238
L
V
C
Y
A
R
I
Y
R
R
L
Q
R
Q
G
Chimpanzee
Pan troglodytes
XP_001156961
346
38879
L238
M
K
Q
V
N
V
V
L
V
V
M
V
V
A
F
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
K247
T
R
I
W
S
K
L
K
S
H
V
S
P
G
A
Dog
Lupus familis
XP_546199
375
42357
Y238
L
V
C
Y
A
R
V
Y
R
H
L
R
K
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61041
375
42616
Y238
L
V
C
Y
I
R
I
Y
Q
R
L
Q
R
Q
K
Rat
Rattus norvegicus
Q63447
375
42550
Y238
L
V
C
Y
M
R
I
Y
Q
R
L
Q
R
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519501
379
43029
H238
L
V
C
Y
L
R
I
H
L
R
L
Q
R
R
R
Chicken
Gallus gallus
Q9DDN6
385
43491
K251
T
R
I
W
T
K
L
K
N
H
V
S
P
G
A
Frog
Xenopus laevis
P34992
366
42234
K247
M
D
K
I
R
D
N
K
Y
R
S
S
E
T
K
Zebra Danio
Brachydanio rerio
NP_571511
375
42098
Q240
E
R
A
R
G
G
R
Q
K
K
A
K
G
S
K
Tiger Blowfish
Takifugu rubipres
NP_001098075
411
46956
V269
L
L
V
L
L
C
Y
V
R
V
F
V
R
L
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18179
455
52169
N246
K
L
R
F
A
N
R
N
Q
N
V
T
T
N
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
31.2
85.5
N.A.
75.7
74.6
N.A.
64.6
29
43.2
50.9
44.2
N.A.
N.A.
24.3
N.A.
Protein Similarity:
100
89.8
49
93.8
N.A.
85
84.2
N.A.
77.3
46.2
61.8
66.4
64.4
N.A.
N.A.
41.3
N.A.
P-Site Identity:
100
0
0
60
N.A.
80
80
N.A.
66.6
0
6.6
0
20
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
33.3
86.6
N.A.
86.6
86.6
N.A.
80
26.6
13.3
20
26.6
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
25
0
0
0
0
0
9
0
0
9
17
% A
% Cys:
0
0
42
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% F
% Gly:
0
0
0
0
9
9
0
0
0
0
0
0
9
17
9
% G
% His:
0
0
0
0
0
0
0
9
0
25
0
0
0
0
0
% H
% Ile:
0
0
17
9
9
0
34
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
9
0
0
17
0
25
9
9
0
9
9
0
34
% K
% Leu:
50
17
0
9
17
0
17
9
9
0
42
0
0
9
0
% L
% Met:
17
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
9
9
9
9
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% P
% Gln:
0
0
9
0
0
0
0
9
25
0
0
34
0
25
0
% Q
% Arg:
0
25
9
9
9
42
17
0
25
42
0
9
42
17
25
% R
% Ser:
0
0
0
0
9
0
0
0
9
0
9
25
0
9
0
% S
% Thr:
17
0
0
0
9
0
0
0
0
0
0
9
9
9
9
% T
% Val:
0
42
9
9
0
9
17
9
9
17
25
17
9
0
0
% V
% Trp:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
42
0
0
9
34
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _