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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GDI2 All Species: 37.58
Human Site: Y111 Identified Species: 75.15
UniProt: P50395 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50395 NP_001108628.1 445 50663 Y111 V T E G S F V Y K G G K I Y K
Chimpanzee Pan troglodytes XP_507638 754 84691 Y417 V T E G S F V Y K G G K I Y K
Rhesus Macaque Macaca mulatta XP_001105854 445 50689 Y111 V T E G S F V Y K G G K I Y K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q61598 445 50519 Y111 V I E G S F V Y K G G K I Y K
Rat Rattus norvegicus P50398 447 50518 Y111 V V E G S F V Y K G G K I Y K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516117 557 61407 Y220 V T E G S F V Y K G G K I Y K
Chicken Gallus gallus NP_990335 448 50664 Y111 V I E G S F V Y K G G K I Y K
Frog Xenopus laevis NP_001080236 446 50524 Y111 V I E G S F V Y K G G K I Y K
Zebra Danio Brachydanio rerio NP_955949 448 50496 Y111 V I E G S F V Y K K G S I Y K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V8W3 511 56809 F102 V L A K S R R F S L D L C P R
Honey Bee Apis mellifera XP_623197 442 49768 Y110 C V E G S Y V Y K S G K I S K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39958 451 51188 F119 Q V S G S Y V F K Q G K I Y K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.7 99.5 N.A. N.A. 96.4 86.8 N.A. 74.3 93 89.4 88.6 N.A. 21.9 68.5 N.A. N.A.
Protein Similarity: 100 58.8 99.7 N.A. N.A. 98.6 94.4 N.A. 76.4 95.9 95.9 94.8 N.A. 43.2 81.8 N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. 100 93.3 93.3 80 N.A. 13.3 66.6 N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. 100 93.3 93.3 80 N.A. 26.6 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 54.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 75.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 60 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 84 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 75 0 17 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 92 0 0 0 0 0 67 92 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 34 0 0 0 0 0 0 0 0 0 0 92 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 92 9 0 84 0 0 92 % K
% Leu: 0 9 0 0 0 0 0 0 0 9 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 9 % R
% Ser: 0 0 9 0 100 0 0 0 9 9 0 9 0 9 0 % S
% Thr: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 84 25 0 0 0 0 92 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 17 0 84 0 0 0 0 0 84 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _