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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EMD
All Species:
19.39
Human Site:
S186
Identified Species:
47.41
UniProt:
P50402
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50402
NP_000108.1
254
28994
S186
L
S
Y
Y
P
T
S
S
S
T
S
F
M
S
S
Chimpanzee
Pan troglodytes
XP_521335
277
30895
S209
L
S
Y
Y
P
T
S
S
S
T
S
F
M
S
S
Rhesus Macaque
Macaca mulatta
XP_001090376
258
29405
S186
L
S
Y
Y
P
T
S
S
S
T
S
S
M
S
S
Dog
Lupus familis
XP_549369
252
26911
S187
S
T
S
P
I
S
S
S
S
S
S
P
T
S
W
Cat
Felis silvestris
Mouse
Mus musculus
O08579
259
29417
S186
G
L
S
Y
Y
P
T
S
S
T
S
S
V
S
S
Rat
Rattus norvegicus
Q63190
260
29657
S187
G
L
S
Y
Y
P
R
S
S
T
S
S
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508363
311
34677
S225
S
S
S
P
L
G
P
S
A
Y
S
A
Y
S
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089080
180
21644
K142
Q
N
E
E
K
P
C
K
R
Y
F
P
A
W
L
Zebra Danio
Brachydanio rerio
XP_001924046
182
20782
S144
Q
S
A
E
S
T
K
S
A
G
V
P
A
W
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01971
166
18100
G128
S
N
K
G
G
F
L
G
S
T
I
T
F
T
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.6
91
44
N.A.
74.5
74.2
N.A.
45
N.A.
27.1
26.7
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
100
81.2
93
55.1
N.A.
83.4
83
N.A.
56.2
N.A.
42.1
42.1
N.A.
N.A.
N.A.
38.1
N.A.
P-Site Identity:
100
100
93.3
33.3
N.A.
46.6
46.6
N.A.
26.6
N.A.
0
20
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
53.3
N.A.
60
53.3
N.A.
40
N.A.
6.6
26.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
20
0
0
10
20
0
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
20
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
10
20
10
0
0
% F
% Gly:
20
0
0
10
10
10
0
10
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
10
% I
% Lys:
0
0
10
0
10
0
10
10
0
0
0
0
0
0
0
% K
% Leu:
30
20
0
0
10
0
10
0
0
0
0
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
0
% M
% Asn:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
20
30
30
10
0
0
0
0
30
0
0
0
% P
% Gln:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% R
% Ser:
30
50
40
0
10
10
40
80
70
10
70
30
0
70
50
% S
% Thr:
0
10
0
0
0
40
10
0
0
60
0
10
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
10
% W
% Tyr:
0
0
30
50
20
0
0
0
0
20
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _