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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR6
All Species:
5.45
Human Site:
S21
Identified Species:
10
UniProt:
P50406
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50406
NP_000862.1
440
46954
S21
A
W
G
A
G
P
P
S
A
P
G
G
S
G
W
Chimpanzee
Pan troglodytes
Q5IS65
440
46934
S21
A
W
G
A
G
P
P
S
A
P
G
G
S
G
W
Rhesus Macaque
Macaca mulatta
O77680
446
49274
S21
L
V
V
E
R
D
F
S
V
R
I
L
T
A
C
Dog
Lupus familis
XP_544528
368
39725
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C8
440
46980
P21
A
W
G
P
G
P
P
P
A
P
G
G
S
G
W
Rat
Rattus norvegicus
P31388
436
46904
P21
A
W
G
P
G
P
P
P
A
P
G
G
S
G
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515752
436
47620
G21
R
R
A
W
S
R
Q
G
S
G
S
W
P
W
G
Chicken
Gallus gallus
XP_427576
433
47582
G21
G
E
R
S
L
L
V
G
S
S
W
V
A
A
F
Frog
Xenopus laevis
P42289
451
50531
V23
E
R
E
S
S
F
R
V
L
T
G
C
F
L
S
Zebra Danio
Brachydanio rerio
XP_696681
471
51696
I35
T
I
S
D
G
W
S
I
G
G
S
G
P
W
L
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
G35
D
V
P
A
P
V
G
G
V
S
V
R
A
L
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
S21
D
Q
P
E
N
T
F
S
L
L
S
V
L
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784371
461
52045
M43
P
A
D
P
D
G
G
M
P
I
V
Q
M
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.8
69.3
N.A.
88.4
76.1
N.A.
65.6
61.1
29.2
51.5
33
N.A.
31.3
N.A.
31.6
Protein Similarity:
100
99.7
47.9
72.2
N.A.
91.5
80
N.A.
74.7
71.1
46.7
60
48.6
N.A.
46.8
N.A.
47.9
P-Site Identity:
100
100
6.6
0
N.A.
86.6
86.6
N.A.
0
0
6.6
13.3
6.6
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
13.3
0
N.A.
86.6
86.6
N.A.
6.6
26.6
13.3
13.3
13.3
N.A.
6.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
8
8
24
0
0
0
0
31
0
0
0
16
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
16
0
8
8
8
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
8
16
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
16
0
0
0
0
0
8
0
8
% F
% Gly:
8
0
31
0
39
8
16
24
8
16
39
39
0
31
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
8
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
8
8
0
0
16
8
0
8
8
24
16
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
16
24
8
31
31
16
8
31
0
0
16
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
8
16
8
0
8
8
8
0
0
8
0
8
0
0
0
% R
% Ser:
0
0
8
16
16
0
8
31
16
16
24
0
31
0
8
% S
% Thr:
8
0
0
0
0
8
0
0
0
8
0
0
8
0
8
% T
% Val:
0
16
8
0
0
8
8
8
16
0
16
16
0
8
8
% V
% Trp:
0
31
0
8
0
8
0
0
0
0
8
8
0
16
31
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _