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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR6
All Species:
15.45
Human Site:
S249
Identified Species:
28.33
UniProt:
P50406
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50406
NP_000862.1
440
46954
S249
T
P
R
P
G
V
E
S
A
D
S
R
R
L
A
Chimpanzee
Pan troglodytes
Q5IS65
440
46934
S249
T
P
R
P
G
V
E
S
A
D
S
R
R
L
A
Rhesus Macaque
Macaca mulatta
O77680
446
49274
P256
K
P
V
E
C
S
Q
P
E
S
S
F
K
M
S
Dog
Lupus familis
XP_544528
368
39725
S205
P
G
M
E
S
A
D
S
R
R
L
A
T
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C8
440
46980
S251
T
P
R
P
G
M
E
S
A
D
S
R
R
L
T
Rat
Rattus norvegicus
P31388
436
46904
S249
T
P
R
P
G
M
E
S
A
D
S
R
R
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515752
436
47620
P255
P
L
Q
V
P
R
T
P
T
D
N
R
R
F
V
Chicken
Gallus gallus
XP_427576
433
47582
G254
A
P
S
Q
P
A
A
G
S
E
S
R
R
F
A
Frog
Xenopus laevis
P42289
451
50531
K264
S
S
L
K
T
S
F
K
R
E
T
K
V
L
K
Zebra Danio
Brachydanio rerio
XP_696681
471
51696
I289
P
P
S
P
G
H
A
I
Q
D
G
D
D
Y
S
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
K263
T
H
D
E
S
A
L
K
T
S
F
K
R
E
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
T235
A
V
T
K
L
P
D
T
S
M
A
K
S
F
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784371
461
52045
I278
M
I
S
I
Y
A
C
I
F
K
A
V
R
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.8
69.3
N.A.
88.4
76.1
N.A.
65.6
61.1
29.2
51.5
33
N.A.
31.3
N.A.
31.6
Protein Similarity:
100
99.7
47.9
72.2
N.A.
91.5
80
N.A.
74.7
71.1
46.7
60
48.6
N.A.
46.8
N.A.
47.9
P-Site Identity:
100
100
13.3
6.6
N.A.
86.6
93.3
N.A.
20
33.3
6.6
26.6
13.3
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
40
13.3
N.A.
93.3
100
N.A.
33.3
46.6
33.3
33.3
20
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
31
16
0
31
0
16
8
0
0
31
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
16
0
0
47
0
8
8
0
0
% D
% Glu:
0
0
0
24
0
0
31
0
8
16
0
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
8
0
8
0
8
8
0
24
0
% F
% Gly:
0
8
0
0
39
0
0
8
0
0
8
0
0
0
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
8
0
0
0
16
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
16
0
0
0
16
0
8
0
24
8
8
8
% K
% Leu:
0
8
8
0
8
0
8
0
0
0
8
0
0
39
0
% L
% Met:
8
0
8
0
0
16
0
0
0
8
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
24
54
0
39
16
8
0
16
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
8
0
0
8
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
31
0
0
8
0
0
16
8
0
47
62
0
8
% R
% Ser:
8
8
24
0
16
16
0
39
16
16
47
0
8
0
16
% S
% Thr:
39
0
8
0
8
0
8
8
16
0
8
0
8
0
16
% T
% Val:
0
8
8
8
0
16
0
0
0
0
0
8
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _