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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR6
All Species:
21.21
Human Site:
S260
Identified Species:
38.89
UniProt:
P50406
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50406
NP_000862.1
440
46954
S260
R
R
L
A
T
K
H
S
R
K
A
L
K
A
S
Chimpanzee
Pan troglodytes
Q5IS65
440
46934
S260
R
R
L
A
T
K
H
S
R
K
A
L
K
A
S
Rhesus Macaque
Macaca mulatta
O77680
446
49274
E267
F
K
M
S
F
K
R
E
T
K
V
L
K
T
L
Dog
Lupus familis
XP_544528
368
39725
A216
A
T
K
H
S
R
K
A
L
K
A
S
L
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C8
440
46980
S262
R
R
L
T
T
K
H
S
R
K
A
L
K
A
S
Rat
Rattus norvegicus
P31388
436
46904
S260
R
R
L
A
T
K
H
S
R
K
A
L
K
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515752
436
47620
S266
R
R
F
V
T
K
H
S
R
K
A
L
K
A
S
Chicken
Gallus gallus
XP_427576
433
47582
S265
R
R
F
A
N
K
H
S
K
K
A
L
K
A
S
Frog
Xenopus laevis
P42289
451
50531
V275
K
V
L
K
T
L
S
V
I
M
G
V
F
V
C
Zebra Danio
Brachydanio rerio
XP_696681
471
51696
P300
D
D
Y
S
H
Q
E
P
P
G
L
R
H
A
P
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
K274
K
R
E
T
K
V
L
K
T
L
S
V
I
M
G
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
H246
K
S
F
V
R
K
V
H
A
T
K
P
P
K
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784371
461
52045
A289
V
R
E
R
M
R
N
A
R
L
G
R
L
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.8
69.3
N.A.
88.4
76.1
N.A.
65.6
61.1
29.2
51.5
33
N.A.
31.3
N.A.
31.6
Protein Similarity:
100
99.7
47.9
72.2
N.A.
91.5
80
N.A.
74.7
71.1
46.7
60
48.6
N.A.
46.8
N.A.
47.9
P-Site Identity:
100
100
26.6
13.3
N.A.
93.3
100
N.A.
86.6
80
13.3
6.6
6.6
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
46.6
33.3
N.A.
93.3
100
N.A.
86.6
86.6
26.6
20
26.6
N.A.
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
31
0
0
0
16
8
0
54
0
0
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
16
0
0
0
8
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
24
0
8
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
16
0
0
8
8
% G
% His:
0
0
0
8
8
0
47
8
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
24
8
8
8
8
62
8
8
8
62
8
0
54
8
0
% K
% Leu:
0
0
39
0
0
8
8
0
8
16
8
54
16
0
16
% L
% Met:
0
0
8
0
8
0
0
0
0
8
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
0
8
8
0
16
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
47
62
0
8
8
16
8
0
47
0
0
16
0
0
0
% R
% Ser:
0
8
0
16
8
0
8
47
0
0
8
8
0
0
54
% S
% Thr:
0
8
0
16
47
0
0
0
16
8
0
0
0
16
0
% T
% Val:
8
8
0
16
0
8
8
8
0
0
8
16
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _