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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR6
All Species:
13.33
Human Site:
S356
Identified Species:
24.44
UniProt:
P50406
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50406
NP_000862.1
440
46954
S356
A
S
P
S
L
R
T
S
H
S
G
P
R
P
G
Chimpanzee
Pan troglodytes
Q5IS65
440
46934
S356
A
S
P
S
L
R
T
S
H
S
G
P
R
P
G
Rhesus Macaque
Macaca mulatta
O77680
446
49274
S373
N
G
A
A
M
F
S
S
H
H
E
P
R
G
S
Dog
Lupus familis
XP_544528
368
39725
V297
P
G
L
S
L
Q
H
V
L
P
L
P
L
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C8
440
46980
W356
S
P
A
S
P
S
M
W
T
S
H
S
G
A
R
Rat
Rattus norvegicus
P31388
436
46904
T357
P
P
P
C
G
P
L
T
A
V
P
D
Q
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515752
436
47620
S362
I
S
L
S
A
R
N
S
H
S
G
P
R
L
G
Chicken
Gallus gallus
XP_427576
433
47582
K359
S
A
I
S
L
S
M
K
N
S
N
S
G
P
R
Frog
Xenopus laevis
P42289
451
50531
T363
T
S
N
N
I
I
E
T
V
S
I
N
N
N
G
Zebra Danio
Brachydanio rerio
XP_696681
471
51696
S400
A
R
L
L
P
C
C
S
S
S
Q
A
P
R
R
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
E367
Q
A
V
D
F
S
N
E
L
V
S
Y
H
H
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
F328
N
P
I
I
Y
S
I
F
N
T
E
F
R
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784371
461
52045
F381
Y
S
I
F
N
Q
D
F
R
N
A
F
K
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.8
69.3
N.A.
88.4
76.1
N.A.
65.6
61.1
29.2
51.5
33
N.A.
31.3
N.A.
31.6
Protein Similarity:
100
99.7
47.9
72.2
N.A.
91.5
80
N.A.
74.7
71.1
46.7
60
48.6
N.A.
46.8
N.A.
47.9
P-Site Identity:
100
100
26.6
26.6
N.A.
13.3
6.6
N.A.
66.6
26.6
20
20
0
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
46.6
33.3
N.A.
20
20
N.A.
66.6
46.6
40
20
6.6
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
16
16
8
8
0
0
0
8
0
8
8
0
16
8
% A
% Cys:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
8
% D
% Glu:
0
0
0
0
0
0
8
8
0
0
16
0
0
8
0
% E
% Phe:
0
0
0
8
8
8
0
16
0
0
0
16
0
0
0
% F
% Gly:
0
16
0
0
8
0
0
0
0
0
24
0
16
8
31
% G
% His:
0
0
0
0
0
0
8
0
31
8
8
0
8
8
0
% H
% Ile:
8
0
24
8
8
8
8
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% K
% Leu:
0
0
24
8
31
0
8
0
16
0
8
0
8
8
0
% L
% Met:
0
0
0
0
8
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
8
8
8
0
16
0
16
8
8
8
8
16
0
% N
% Pro:
16
24
24
0
16
8
0
0
0
8
8
39
8
31
8
% P
% Gln:
8
0
0
0
0
16
0
0
0
0
8
0
8
0
0
% Q
% Arg:
0
8
0
0
0
24
0
0
8
0
0
0
39
8
24
% R
% Ser:
16
39
0
47
0
31
8
39
8
54
8
16
0
0
16
% S
% Thr:
8
0
0
0
0
0
16
16
8
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
8
8
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _