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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HTR6 All Species: 11.52
Human Site: S382 Identified Species: 21.11
UniProt: P50406 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50406 NP_000862.1 440 46954 S382 P P D S D S D S D A G S G G S
Chimpanzee Pan troglodytes Q5IS65 440 46934 S382 P P D S D S D S D A G S G G S
Rhesus Macaque Macaca mulatta O77680 446 49274 E399 P H A V G S S E D L K K E E A
Dog Lupus familis XP_544528 368 39725 T323 G S S G Q Q R T A Q P L L P R
Cat Felis silvestris
Mouse Mus musculus Q9R1C8 440 46980 S382 P L P P N S D S D S A S G G T
Rat Rattus norvegicus P31388 436 46904 L383 Q T Q I Q T P L Q G A P R A C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515752 436 47620 V388 E T D S G D S V L Q V T D H L
Chicken Gallus gallus XP_427576 433 47582 V385 Q A E T D S V V S E V V A N E
Frog Xenopus laevis P42289 451 50531 N389 G S I P N E C N L V Y L I P H
Zebra Danio Brachydanio rerio XP_696681 471 51696 S426 S G E P Q L P S E P P S L V S
Tiger Blowfish Takifugu rubipres P53454 463 51077 P393 G A H R L V A P L P Q N R G D
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera NP_001011595 402 44536 S354 R G N Q P S T S E C G E F R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784371 461 52045 K407 C W D K R P R K R H R G H H S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 29.8 69.3 N.A. 88.4 76.1 N.A. 65.6 61.1 29.2 51.5 33 N.A. 31.3 N.A. 31.6
Protein Similarity: 100 99.7 47.9 72.2 N.A. 91.5 80 N.A. 74.7 71.1 46.7 60 48.6 N.A. 46.8 N.A. 47.9
P-Site Identity: 100 100 20 0 N.A. 53.3 0 N.A. 13.3 13.3 0 20 6.6 N.A. 26.6 N.A. 13.3
P-Site Similarity: 100 100 26.6 6.6 N.A. 73.3 6.6 N.A. 20 26.6 13.3 33.3 13.3 N.A. 40 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 8 0 0 0 8 0 8 16 16 0 8 8 8 % A
% Cys: 8 0 0 0 0 0 8 0 0 8 0 0 0 0 8 % C
% Asp: 0 0 31 0 24 8 24 0 31 0 0 0 8 0 8 % D
% Glu: 8 0 16 0 0 8 0 8 16 8 0 8 8 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 24 16 0 8 16 0 0 0 0 8 24 8 24 31 0 % G
% His: 0 8 8 0 0 0 0 0 0 8 0 0 8 16 8 % H
% Ile: 0 0 8 8 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 8 0 0 0 8 0 0 8 8 0 0 0 % K
% Leu: 0 8 0 0 8 8 0 8 24 8 0 16 16 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 16 0 0 8 0 0 0 8 0 8 0 % N
% Pro: 31 16 8 24 8 8 16 8 0 16 16 8 0 16 0 % P
% Gln: 16 0 8 8 24 8 0 0 8 16 8 0 0 0 0 % Q
% Arg: 8 0 0 8 8 0 16 0 8 0 8 0 16 8 8 % R
% Ser: 8 16 8 24 0 47 16 39 8 8 0 31 0 0 39 % S
% Thr: 0 16 0 8 0 8 8 8 0 0 0 8 0 0 8 % T
% Val: 0 0 0 8 0 8 8 16 0 8 16 8 0 8 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _