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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR6
All Species:
14.85
Human Site:
T242
Identified Species:
27.22
UniProt:
P50406
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50406
NP_000862.1
440
46954
T242
E
T
L
Q
V
P
R
T
P
R
P
G
V
E
S
Chimpanzee
Pan troglodytes
Q5IS65
440
46934
T242
E
T
L
Q
V
P
R
T
P
R
P
G
V
E
S
Rhesus Macaque
Macaca mulatta
O77680
446
49274
K249
Q
T
T
T
G
N
G
K
P
V
E
C
S
Q
P
Dog
Lupus familis
XP_544528
368
39725
P198
K
V
P
R
T
P
R
P
G
M
E
S
A
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C8
440
46980
T244
E
T
L
Q
V
P
R
T
P
R
P
G
M
E
S
Rat
Rattus norvegicus
P31388
436
46904
T242
E
T
L
Q
V
P
R
T
P
R
P
G
M
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515752
436
47620
P248
V
A
G
P
S
D
D
P
L
Q
V
P
R
T
P
Chicken
Gallus gallus
XP_427576
433
47582
A247
S
M
E
Q
V
P
H
A
P
S
Q
P
A
A
G
Frog
Xenopus laevis
P42289
451
50531
S257
L
D
C
Q
Q
P
E
S
S
L
K
T
S
F
K
Zebra Danio
Brachydanio rerio
XP_696681
471
51696
P282
S
L
G
E
P
S
R
P
P
S
P
G
H
A
I
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
T256
N
Q
S
H
R
A
S
T
H
D
E
S
A
L
K
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
A228
K
H
V
K
S
I
R
A
V
T
K
L
P
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784371
461
52045
M271
F
I
I
P
C
L
I
M
I
S
I
Y
A
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.8
69.3
N.A.
88.4
76.1
N.A.
65.6
61.1
29.2
51.5
33
N.A.
31.3
N.A.
31.6
Protein Similarity:
100
99.7
47.9
72.2
N.A.
91.5
80
N.A.
74.7
71.1
46.7
60
48.6
N.A.
46.8
N.A.
47.9
P-Site Identity:
100
100
13.3
20
N.A.
93.3
93.3
N.A.
0
26.6
13.3
26.6
6.6
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
26.6
40
N.A.
100
100
N.A.
6.6
26.6
20
33.3
6.6
N.A.
40
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
16
0
0
0
0
31
16
0
% A
% Cys:
0
0
8
0
8
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
8
0
0
0
8
8
0
0
8
0
0
0
16
0
% D
% Glu:
31
0
8
8
0
0
8
0
0
0
24
0
0
31
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
16
0
8
0
8
0
8
0
0
39
0
0
8
% G
% His:
0
8
0
8
0
0
8
0
8
0
0
0
8
0
0
% H
% Ile:
0
8
8
0
0
8
8
0
8
0
8
0
0
0
16
% I
% Lys:
16
0
0
8
0
0
0
8
0
0
16
0
0
0
16
% K
% Leu:
8
8
31
0
0
8
0
0
8
8
0
8
0
8
0
% L
% Met:
0
8
0
0
0
0
0
8
0
8
0
0
16
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
16
8
54
0
24
54
0
39
16
8
0
16
% P
% Gln:
8
8
0
47
8
0
0
0
0
8
8
0
0
8
0
% Q
% Arg:
0
0
0
8
8
0
54
0
0
31
0
0
8
0
0
% R
% Ser:
16
0
8
0
16
8
8
8
8
24
0
16
16
0
39
% S
% Thr:
0
39
8
8
8
0
0
39
0
8
0
8
0
8
8
% T
% Val:
8
8
8
0
39
0
0
0
8
8
8
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _