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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR6
All Species:
11.21
Human Site:
T405
Identified Species:
20.56
UniProt:
P50406
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50406
NP_000862.1
440
46954
T405
L
L
L
P
G
E
A
T
Q
D
P
P
L
P
T
Chimpanzee
Pan troglodytes
Q5IS65
440
46934
T405
L
L
L
P
G
E
A
T
R
D
P
P
L
P
T
Rhesus Macaque
Macaca mulatta
O77680
446
49274
V422
K
L
S
P
A
L
S
V
I
L
D
Y
D
T
D
Dog
Lupus familis
XP_544528
368
39725
V346
P
T
R
V
A
A
V
V
N
F
F
N
I
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C8
440
46980
T405
L
L
L
P
G
E
A
T
R
D
P
P
P
P
T
Rat
Rattus norvegicus
P31388
436
46904
P406
L
E
R
P
P
G
T
P
R
H
P
P
G
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515752
436
47620
A411
D
P
L
P
P
R
G
A
D
S
V
N
L
F
D
Chicken
Gallus gallus
XP_427576
433
47582
A408
G
A
L
P
A
P
S
A
H
L
V
G
L
F
E
Frog
Xenopus laevis
P42289
451
50531
S412
V
L
K
K
E
D
E
S
G
L
S
K
S
L
E
Zebra Danio
Brachydanio rerio
XP_696681
471
51696
L449
A
T
D
A
V
N
L
L
D
A
E
H
A
G
I
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
R416
S
V
V
S
D
D
S
R
A
D
R
N
L
L
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
S377
S
M
I
E
C
N
I
S
P
R
S
S
A
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784371
461
52045
R430
N
D
I
N
G
R
V
R
F
D
A
P
A
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.8
69.3
N.A.
88.4
76.1
N.A.
65.6
61.1
29.2
51.5
33
N.A.
31.3
N.A.
31.6
Protein Similarity:
100
99.7
47.9
72.2
N.A.
91.5
80
N.A.
74.7
71.1
46.7
60
48.6
N.A.
46.8
N.A.
47.9
P-Site Identity:
100
93.3
13.3
0
N.A.
86.6
33.3
N.A.
20
20
6.6
0
13.3
N.A.
0
N.A.
20
P-Site Similarity:
100
100
20
6.6
N.A.
93.3
40
N.A.
20
26.6
26.6
0
40
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
24
8
24
16
8
8
8
0
24
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
8
16
0
0
16
39
8
0
8
16
16
% D
% Glu:
0
8
0
8
8
24
8
0
0
0
8
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
8
0
0
16
0
% F
% Gly:
8
0
0
0
31
8
8
0
8
0
0
8
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% H
% Ile:
0
0
16
0
0
0
8
0
8
0
0
0
8
0
8
% I
% Lys:
8
0
8
8
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
31
39
39
0
0
8
8
8
0
24
0
0
39
16
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
16
0
0
8
0
0
24
0
0
0
% N
% Pro:
8
8
0
54
16
8
0
8
8
0
31
39
8
31
16
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
16
0
0
16
0
16
24
8
8
0
0
0
0
% R
% Ser:
16
0
8
8
0
0
24
16
0
8
16
8
8
0
8
% S
% Thr:
0
16
0
0
0
0
8
24
0
0
0
0
0
8
24
% T
% Val:
8
8
8
8
8
0
16
16
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _