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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HTR6 All Species: 6.97
Human Site: T8 Identified Species: 12.78
UniProt: P50406 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50406 NP_000862.1 440 46954 T8 M V P E P G P T A N S T P A W
Chimpanzee Pan troglodytes Q5IS65 440 46934 S8 M V P E P G P S A N S T P A W
Rhesus Macaque Macaca mulatta O77680 446 49274 A8 M R T L N T S A M D G T G L V
Dog Lupus familis XP_544528 368 39725
Cat Felis silvestris
Mouse Mus musculus Q9R1C8 440 46980 V8 M V P E P G P V N S S T P A W
Rat Rattus norvegicus P31388 436 46904 V8 M V P E P G P V N S S T P A W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515752 436 47620 A8 M G G W S Q K A R G E V G R R
Chicken Gallus gallus XP_427576 433 47582 P8 M E G N L G S P N A S V L G E
Frog Xenopus laevis P42289 451 50531 E10 F N I T S M D E D V L L T E R
Zebra Danio Brachydanio rerio XP_696681 471 51696 S22 D L W K I H R S F N D S S T I
Tiger Blowfish Takifugu rubipres P53454 463 51077 V22 G G V D P L R V V T A A E D V
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera NP_001011595 402 44536 L8 M I L S Q N N L T D G K E D Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784371 461 52045 Y30 L S M S E Y D Y S T E E P P A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 29.8 69.3 N.A. 88.4 76.1 N.A. 65.6 61.1 29.2 51.5 33 N.A. 31.3 N.A. 31.6
Protein Similarity: 100 99.7 47.9 72.2 N.A. 91.5 80 N.A. 74.7 71.1 46.7 60 48.6 N.A. 46.8 N.A. 47.9
P-Site Identity: 100 93.3 13.3 0 N.A. 80 80 N.A. 6.6 20 0 6.6 6.6 N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 20 0 N.A. 86.6 86.6 N.A. 6.6 20 0 33.3 20 N.A. 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 16 16 8 8 8 0 31 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 0 0 16 0 8 16 8 0 0 16 0 % D
% Glu: 0 8 0 31 8 0 0 8 0 0 16 8 16 8 8 % E
% Phe: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 8 16 16 0 0 39 0 0 0 8 16 0 16 8 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 8 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 8 0 0 8 0 0 0 0 8 0 0 0 % K
% Leu: 8 8 8 8 8 8 0 8 0 0 8 8 8 8 0 % L
% Met: 62 0 8 0 0 8 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 8 8 8 0 24 24 0 0 0 0 0 % N
% Pro: 0 0 31 0 39 0 31 8 0 0 0 0 39 8 0 % P
% Gln: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 8 0 0 0 0 16 0 8 0 0 0 0 8 16 % R
% Ser: 0 8 0 16 16 0 16 16 8 16 39 8 8 0 0 % S
% Thr: 0 0 8 8 0 8 0 8 8 16 0 39 8 8 0 % T
% Val: 0 31 8 0 0 0 0 24 8 8 0 16 0 0 16 % V
% Trp: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 31 % W
% Tyr: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _