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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR6
All Species:
40.3
Human Site:
Y125
Identified Species:
73.89
UniProt:
P50406
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50406
NP_000862.1
440
46954
Y125
C
L
I
S
L
D
R
Y
L
L
I
L
S
P
L
Chimpanzee
Pan troglodytes
Q5IS65
440
46934
Y125
C
L
I
S
L
D
R
Y
L
L
I
L
S
P
L
Rhesus Macaque
Macaca mulatta
O77680
446
49274
Y122
C
V
I
S
V
D
R
Y
W
A
I
S
S
P
F
Dog
Lupus familis
XP_544528
368
39725
H94
L
P
L
L
L
G
W
H
Q
L
G
R
A
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C8
440
46980
Y125
C
L
I
S
L
D
R
Y
L
L
I
L
S
P
L
Rat
Rattus norvegicus
P31388
436
46904
Y125
C
L
I
S
L
D
R
Y
L
L
I
L
S
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515752
436
47620
Y125
C
L
I
S
L
D
R
Y
L
L
I
L
S
P
L
Chicken
Gallus gallus
XP_427576
433
47582
Y130
L
I
I
S
P
L
K
Y
K
L
R
M
T
S
C
Frog
Xenopus laevis
P42289
451
50531
Y130
A
I
S
S
P
F
R
Y
E
R
K
M
T
P
K
Zebra Danio
Brachydanio rerio
XP_696681
471
51696
Y139
C
V
I
S
L
D
R
Y
L
L
I
I
S
P
L
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
Y138
C
V
I
S
M
D
R
Y
W
A
I
S
N
P
F
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
Y124
C
A
I
S
L
D
R
Y
I
H
I
K
D
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784371
461
52045
Y147
C
A
I
S
V
D
R
Y
I
H
I
K
R
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.8
69.3
N.A.
88.4
76.1
N.A.
65.6
61.1
29.2
51.5
33
N.A.
31.3
N.A.
31.6
Protein Similarity:
100
99.7
47.9
72.2
N.A.
91.5
80
N.A.
74.7
71.1
46.7
60
48.6
N.A.
46.8
N.A.
47.9
P-Site Identity:
100
100
60
13.3
N.A.
100
100
N.A.
100
26.6
26.6
86.6
53.3
N.A.
66.6
N.A.
53.3
P-Site Similarity:
100
100
73.3
33.3
N.A.
100
100
N.A.
100
53.3
46.6
100
73.3
N.A.
73.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
0
0
0
0
0
0
16
0
0
8
0
8
% A
% Cys:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
77
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
24
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
16
0
0
0
0
0
% H
% Ile:
0
16
85
0
0
0
0
0
16
0
77
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
8
0
8
16
0
0
8
% K
% Leu:
16
39
8
8
62
8
0
0
47
62
0
39
0
0
54
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
16
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
8
0
0
16
0
0
0
0
0
0
0
0
85
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
85
0
0
8
8
8
8
8
0
% R
% Ser:
0
0
8
93
0
0
0
0
0
0
0
16
54
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% T
% Val:
0
24
0
0
16
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
16
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _