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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR6
All Species:
27.27
Human Site:
Y310
Identified Species:
50
UniProt:
P50406
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50406
NP_000862.1
440
46954
Y310
D
V
L
T
W
L
G
Y
C
N
S
T
M
N
P
Chimpanzee
Pan troglodytes
Q5IS65
440
46934
Y310
D
V
L
T
W
L
G
Y
C
N
S
T
M
N
P
Rhesus Macaque
Macaca mulatta
O77680
446
49274
W321
D
V
F
V
W
F
G
W
A
N
S
S
L
N
P
Dog
Lupus familis
XP_544528
368
39725
Y263
D
V
L
T
W
L
G
Y
C
N
S
T
M
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C8
440
46980
Y312
D
V
L
T
W
L
G
Y
C
N
S
T
M
N
P
Rat
Rattus norvegicus
P31388
436
46904
Y310
D
V
L
T
W
L
G
Y
C
N
S
T
M
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515752
436
47620
Y316
D
I
L
T
W
L
G
Y
C
N
S
T
M
N
P
Chicken
Gallus gallus
XP_427576
433
47582
Y315
D
V
L
T
W
L
G
Y
C
N
S
T
M
N
P
Frog
Xenopus laevis
P42289
451
50531
W324
D
V
F
V
W
F
G
W
A
N
S
S
L
N
P
Zebra Danio
Brachydanio rerio
XP_696681
471
51696
Q352
F
F
I
T
N
M
A
Q
A
V
C
E
C
V
P
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
W324
N
I
F
V
W
F
G
W
A
N
S
S
L
N
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001011595
402
44536
I293
V
P
F
F
C
V
N
I
V
T
S
Y
C
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784371
461
52045
F337
L
M
C
W
L
P
F
F
I
Y
N
I
V
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.8
69.3
N.A.
88.4
76.1
N.A.
65.6
61.1
29.2
51.5
33
N.A.
31.3
N.A.
31.6
Protein Similarity:
100
99.7
47.9
72.2
N.A.
91.5
80
N.A.
74.7
71.1
46.7
60
48.6
N.A.
46.8
N.A.
47.9
P-Site Identity:
100
100
53.3
100
N.A.
100
100
N.A.
93.3
100
53.3
13.3
40
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
100
100
73.3
26.6
73.3
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
31
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
8
0
0
0
54
0
8
0
16
0
0
% C
% Asp:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
8
8
31
8
0
24
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
77
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
8
0
0
0
0
8
8
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
8
0
54
0
8
54
0
0
0
0
0
0
24
8
0
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
54
0
0
% M
% Asn:
8
0
0
0
8
0
8
0
0
77
8
0
0
77
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
93
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
85
24
0
0
0
% S
% Thr:
0
0
0
62
0
0
0
0
0
8
0
54
0
0
8
% T
% Val:
8
62
0
24
0
8
0
0
8
8
0
0
8
8
0
% V
% Trp:
0
0
0
8
77
0
0
24
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _