KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPT1A
All Species:
22.42
Human Site:
S741
Identified Species:
49.33
UniProt:
P50416
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50416
NP_001027017.1
773
88368
S741
F
H
I
S
S
K
F
S
C
P
E
T
D
S
H
Chimpanzee
Pan troglodytes
XP_001173820
773
88331
S741
F
H
I
S
S
K
F
S
C
P
E
T
D
S
H
Rhesus Macaque
Macaca mulatta
XP_001101846
773
88366
S741
F
H
I
S
S
K
F
S
C
P
E
T
D
S
H
Dog
Lupus familis
XP_533208
864
97554
S832
F
H
I
S
S
K
F
S
S
P
E
T
D
S
H
Cat
Felis silvestris
Mouse
Mus musculus
P97742
773
88233
S741
F
H
I
S
S
K
F
S
S
P
E
T
D
S
H
Rat
Rattus norvegicus
P32198
773
88107
S741
F
H
I
S
S
K
F
S
S
P
E
T
D
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YJ9
640
72605
E609
A
V
E
E
S
L
L
E
I
R
D
L
C
N
K
Frog
Xenopus laevis
Q7ZXE1
659
74538
S628
D
W
I
G
C
N
V
S
S
Y
P
A
R
D
V
Zebra Danio
Brachydanio rerio
B2ZGJ1
637
71821
D606
G
C
L
K
E
M
Q
D
L
C
R
K
C
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P32756
627
71299
P596
P
D
R
V
I
F
A
P
T
A
F
R
S
D
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32796
670
77223
G639
V
N
K
P
A
K
S
G
A
S
V
N
R
L
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.2
81.5
N.A.
86.5
86.5
N.A.
N.A.
23.1
22.6
22.7
N.A.
N.A.
N.A.
22.3
N.A.
Protein Similarity:
100
99.6
99
86.3
N.A.
94.5
94.8
N.A.
N.A.
39.8
41.7
39
N.A.
N.A.
N.A.
39.7
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
13.3
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
20
13.3
13.3
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
10
0
10
10
0
10
0
0
0
% A
% Cys:
0
10
0
0
10
0
0
0
28
10
0
0
19
0
0
% C
% Asp:
10
10
0
0
0
0
0
10
0
0
10
0
55
19
0
% D
% Glu:
0
0
10
10
10
0
0
10
0
0
55
0
0
0
0
% E
% Phe:
55
0
0
0
0
10
55
0
0
0
10
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
64
% H
% Ile:
0
0
64
0
10
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
0
64
0
0
0
0
0
10
0
0
10
% K
% Leu:
0
0
10
0
0
10
10
0
10
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
0
10
0
19
0
% N
% Pro:
10
0
0
10
0
0
0
10
0
55
10
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
10
10
10
19
0
0
% R
% Ser:
0
0
0
55
64
0
10
64
37
10
0
0
10
55
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
55
0
0
10
% T
% Val:
10
10
0
10
0
0
10
0
0
0
10
0
0
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _