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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A2 All Species: 10
Human Site: S193 Identified Species: 18.33
UniProt: P50443 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50443 NP_000103.2 739 81662 S193 D N A H S A P S L G M V S N G
Chimpanzee Pan troglodytes XP_001164642 739 81648 S193 D N A H S A P S L G M V S N G
Rhesus Macaque Macaca mulatta XP_001098562 860 94599 I314 M S G L I V G I L L V P Q S I
Dog Lupus familis XP_855107 742 81873 D196 T A D N A P S D L G L V L N G
Cat Felis silvestris
Mouse Mus musculus Q62273 739 81586 S193 D T D A T S S S I A V F S S G
Rat Rattus norvegicus O70531 739 82010 S193 D I D T T S S S I A M F S N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506994 916 100035 G369 E Q A V R A A G P V N G T A G
Chicken Gallus gallus XP_425183 712 78105 K187 P V N Q T S Q K L L C D K T C
Frog Xenopus laevis NP_001084442 719 79740 M187 I N I S M G L M D I E C G K E
Zebra Danio Brachydanio rerio XP_685114 699 76761 C174 D N S T G P I C D R S C Y A I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 P192 M W T E G V T P V K Q I H V A
Sea Urchin Strong. purpuratus XP_793050 822 89984 G200 G F N S S I G G D F P S S G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04722 677 74050 V152 Q Y G L Y T S V V P P L I Y A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 55.9 87 N.A. 80.9 81 N.A. 59.6 67.9 50.2 55.7 N.A. N.A. N.A. 23.6 32.1
Protein Similarity: 100 99.7 64.8 94 N.A. 89.8 89.8 N.A. 69.6 80.9 69.9 72.9 N.A. N.A. N.A. 44.3 53.8
P-Site Identity: 100 100 6.6 33.3 N.A. 26.6 40 N.A. 20 6.6 6.6 13.3 N.A. N.A. N.A. 0 20
P-Site Similarity: 100 100 26.6 53.3 N.A. 60 60 N.A. 33.3 20 6.6 20 N.A. N.A. N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 24 8 8 24 8 0 0 16 0 0 0 16 16 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 8 16 0 0 8 % C
% Asp: 39 0 24 0 0 0 0 8 24 0 0 8 0 0 0 % D
% Glu: 8 0 0 8 0 0 0 0 0 0 8 0 0 0 8 % E
% Phe: 0 8 0 0 0 0 0 0 0 8 0 16 0 0 0 % F
% Gly: 8 0 16 0 16 8 16 16 0 24 0 8 8 8 54 % G
% His: 0 0 0 16 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 8 8 0 8 8 8 8 16 8 0 8 8 0 16 % I
% Lys: 0 0 0 0 0 0 0 8 0 8 0 0 8 8 0 % K
% Leu: 0 0 0 16 0 0 8 0 39 16 8 8 8 0 0 % L
% Met: 16 0 0 0 8 0 0 8 0 0 24 0 0 0 0 % M
% Asn: 0 31 16 8 0 0 0 0 0 0 8 0 0 31 0 % N
% Pro: 8 0 0 0 0 16 16 8 8 8 16 8 0 0 0 % P
% Gln: 8 8 0 8 0 0 8 0 0 0 8 0 8 0 0 % Q
% Arg: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 8 8 16 24 24 31 31 0 0 8 8 39 16 0 % S
% Thr: 8 8 8 16 24 8 8 0 0 0 0 0 8 8 0 % T
% Val: 0 8 0 8 0 16 0 8 16 8 16 24 0 8 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 8 0 0 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _