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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A2 All Species: 11.52
Human Site: S208 Identified Species: 21.11
UniProt: P50443 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50443 NP_000103.2 739 81662 S208 S T L L N H T S D R I C D K S
Chimpanzee Pan troglodytes XP_001164642 739 81648 S208 S T L L N H T S D R I C D K S
Rhesus Macaque Macaca mulatta XP_001098562 860 94599 Q329 A Y S L L A G Q E P V Y G L Y
Dog Lupus familis XP_855107 742 81873 S211 S T L L N Q T S D R I C D R S
Cat Felis silvestris
Mouse Mus musculus Q62273 739 81586 L208 C V V V N H T L D G L C D K S
Rat Rattus norvegicus O70531 739 82010 L208 C V V V N H T L D G L C D K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506994 916 100035 S384 P W A A N Q T S G L G C D R S
Chicken Gallus gallus XP_425183 712 78105 T202 Y A I K V G A T V T F I A G V
Frog Xenopus laevis NP_001084442 719 79740 A202 C Y A I S V A A I L T F T A G
Zebra Danio Brachydanio rerio XP_685114 699 76761 F189 M V G A T L T F T A G I Y Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 G207 T T I I F L A G V I Q V F M G
Sea Urchin Strong. purpuratus XP_793050 822 89984 L215 G V E G S T A L F D S G E E A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04722 677 74050 I167 L M G T S R E I A I G P V A V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 55.9 87 N.A. 80.9 81 N.A. 59.6 67.9 50.2 55.7 N.A. N.A. N.A. 23.6 32.1
Protein Similarity: 100 99.7 64.8 94 N.A. 89.8 89.8 N.A. 69.6 80.9 69.9 72.9 N.A. N.A. N.A. 44.3 53.8
P-Site Identity: 100 100 6.6 86.6 N.A. 53.3 53.3 N.A. 40 0 0 6.6 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 26.6 93.3 N.A. 73.3 73.3 N.A. 46.6 13.3 20 13.3 N.A. N.A. N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 16 16 0 8 31 8 8 8 0 0 8 16 8 % A
% Cys: 24 0 0 0 0 0 0 0 0 0 0 47 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 39 8 0 0 47 0 0 % D
% Glu: 0 0 8 0 0 0 8 0 8 0 0 0 8 8 0 % E
% Phe: 0 0 0 0 8 0 0 8 8 0 8 8 8 0 0 % F
% Gly: 8 0 16 8 0 8 8 8 8 16 24 8 8 8 16 % G
% His: 0 0 0 0 0 31 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 16 16 0 0 0 8 8 16 24 16 0 0 0 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 0 0 0 31 0 % K
% Leu: 8 0 24 31 8 16 0 24 0 16 16 0 0 8 0 % L
% Met: 8 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 47 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 16 0 8 0 0 8 0 0 8 0 % Q
% Arg: 0 0 0 0 0 8 0 0 0 24 0 0 0 16 0 % R
% Ser: 24 0 8 0 24 0 0 31 0 0 8 0 0 0 47 % S
% Thr: 8 31 0 8 8 8 54 8 8 8 8 0 8 0 0 % T
% Val: 0 31 16 16 8 8 0 0 16 0 8 8 8 0 24 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 16 0 0 0 0 0 0 0 0 0 8 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _