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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A2 All Species: 7.27
Human Site: S506 Identified Species: 13.33
UniProt: P50443 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50443 NP_000103.2 739 81662 S506 R D L P K M W S I S R M D T V
Chimpanzee Pan troglodytes XP_001164642 739 81648 S506 R D L P K M W S I S R M D T V
Rhesus Macaque Macaca mulatta XP_001098562 860 94599 N627 R D L P K M W N I S R M D T V
Dog Lupus familis XP_855107 742 81873 K509 K D L P K M W K V S R M D T V
Cat Felis silvestris
Mouse Mus musculus Q62273 739 81586 R506 R D L P K M W R L S R M D T V
Rat Rattus norvegicus O70531 739 82010 R506 R D L P K M W R L S R M D T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506994 916 100035 K682 S D L P R M W K L S R I D T V
Chicken Gallus gallus XP_425183 712 78105 W493 S R V D T V I W L V T M A S S
Frog Xenopus laevis NP_001084442 719 79740 W494 N K I D A V V W C V T V A A A
Zebra Danio Brachydanio rerio XP_685114 699 76761 T480 D T V I W L L T M A T S A L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 D548 Y K E T K K R D L E R I Q G N
Sea Urchin Strong. purpuratus XP_793050 822 89984 K514 K D L R D L W K F S K V D C M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04722 677 74050 T458 L T R L L Y Y T P I A I L A S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 55.9 87 N.A. 80.9 81 N.A. 59.6 67.9 50.2 55.7 N.A. N.A. N.A. 23.6 32.1
Protein Similarity: 100 99.7 64.8 94 N.A. 89.8 89.8 N.A. 69.6 80.9 69.9 72.9 N.A. N.A. N.A. 44.3 53.8
P-Site Identity: 100 100 93.3 80 N.A. 86.6 86.6 N.A. 66.6 6.6 0 6.6 N.A. N.A. N.A. 13.3 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 86.6 33.3 20 40 N.A. N.A. N.A. 26.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 8 8 0 24 16 8 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % C
% Asp: 8 62 0 16 8 0 0 8 0 0 0 0 62 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 8 0 24 8 0 24 0 0 0 % I
% Lys: 16 16 0 0 54 8 0 24 0 0 8 0 0 0 0 % K
% Leu: 8 0 62 8 8 16 8 0 39 0 0 0 8 8 0 % L
% Met: 0 0 0 0 0 54 0 0 8 0 0 54 0 0 8 % M
% Asn: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 54 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 39 8 8 8 8 0 8 16 0 0 62 0 0 0 0 % R
% Ser: 16 0 0 0 0 0 0 16 0 62 0 8 0 8 16 % S
% Thr: 0 16 0 8 8 0 0 16 0 0 24 0 0 54 0 % T
% Val: 0 0 16 0 0 16 8 0 8 16 0 16 0 0 62 % V
% Trp: 0 0 0 0 8 0 62 16 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _