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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A2 All Species: 28.18
Human Site: S565 Identified Species: 51.67
UniProt: P50443 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50443 NP_000103.2 739 81662 S565 E E S E V F E S V S A Y K N L
Chimpanzee Pan troglodytes XP_001164642 739 81648 S565 E E S E V F E S V S A Y K N L
Rhesus Macaque Macaca mulatta XP_001098562 860 94599 S686 E E S E V F E S V S A Y K N L
Dog Lupus familis XP_855107 742 81873 S568 E E S E I F E S M S A Y K N L
Cat Felis silvestris
Mouse Mus musculus Q62273 739 81586 S565 E E S E T F E S I S T Y K N L
Rat Rattus norvegicus O70531 739 82010 S565 E E S E I F E S I S T Y K N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506994 916 100035 S741 E E S E T Y E S T A A Y K N L
Chicken Gallus gallus XP_425183 712 78105 T552 S A Y K N L E T K P G V V V L
Frog Xenopus laevis NP_001084442 719 79740 P553 Q K Y D N L L P I P K V K I F
Zebra Danio Brachydanio rerio XP_685114 699 76761 D539 N G L Q T Q P D V A V F R Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 F607 S D R S A D I F D S K L K S A
Sea Urchin Strong. purpuratus XP_793050 822 89984 D573 P N T D I Y R D L S Y Y R A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04722 677 74050 S517 L L V A V V I S F A K I I L I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 55.9 87 N.A. 80.9 81 N.A. 59.6 67.9 50.2 55.7 N.A. N.A. N.A. 23.6 32.1
Protein Similarity: 100 99.7 64.8 94 N.A. 89.8 89.8 N.A. 69.6 80.9 69.9 72.9 N.A. N.A. N.A. 44.3 53.8
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 73.3 13.3 6.6 6.6 N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 86.6 26.6 33.3 33.3 N.A. N.A. N.A. 26.6 53.3
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 0 0 0 0 24 39 0 0 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 16 0 8 0 16 8 0 0 0 0 0 0 % D
% Glu: 54 54 0 54 0 0 62 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 47 0 8 8 0 0 8 0 0 8 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 24 0 16 0 24 0 0 8 8 8 8 % I
% Lys: 0 8 0 8 0 0 0 0 8 0 24 0 70 0 0 % K
% Leu: 8 8 8 0 0 16 8 0 8 0 0 8 0 8 62 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 16 0 0 0 0 0 0 0 0 54 0 % N
% Pro: 8 0 0 0 0 0 8 8 0 16 0 0 0 0 0 % P
% Gln: 8 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 8 0 0 0 0 0 16 0 0 % R
% Ser: 16 0 54 8 0 0 0 62 0 62 0 0 0 8 0 % S
% Thr: 0 0 8 0 24 0 0 8 8 0 16 0 0 0 0 % T
% Val: 0 0 8 0 31 8 0 0 31 0 8 16 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 16 0 0 16 0 0 0 0 8 62 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _