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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC26A2
All Species:
22.42
Human Site:
S640
Identified Species:
41.11
UniProt:
P50443
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50443
NP_000103.2
739
81662
S640
D
E
M
S
V
Q
L
S
H
D
P
L
E
L
H
Chimpanzee
Pan troglodytes
XP_001164642
739
81648
S640
D
E
M
S
V
Q
L
S
H
D
P
L
E
L
H
Rhesus Macaque
Macaca mulatta
XP_001098562
860
94599
S761
D
E
M
S
V
Q
L
S
H
D
P
L
E
L
H
Dog
Lupus familis
XP_855107
742
81873
S643
D
E
V
S
V
Q
L
S
H
D
P
L
E
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q62273
739
81586
S640
D
E
V
S
M
Q
L
S
H
D
P
L
E
V
H
Rat
Rattus norvegicus
O70531
739
82010
S640
D
E
V
S
M
Q
L
S
H
D
P
L
E
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506994
916
100035
V817
E
K
V
S
A
H
L
V
H
E
P
L
A
H
H
Chicken
Gallus gallus
XP_425183
712
78105
I614
S
G
G
N
Q
T
S
I
S
M
E
L
V
S
E
Frog
Xenopus laevis
NP_001084442
719
79740
G616
V
D
A
A
N
N
L
G
Y
G
E
T
Q
I
E
Zebra Danio
Brachydanio rerio
XP_685114
699
76761
N601
Q
E
M
D
A
S
T
N
V
N
L
L
Q
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94225
782
87457
A677
D
L
K
K
L
F
R
A
T
D
F
Y
E
V
V
Sea Urchin
Strong. purpuratus
XP_793050
822
89984
E698
M
D
E
S
E
E
E
E
V
D
P
T
L
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04722
677
74050
I579
A
S
S
I
E
E
R
I
M
G
W
V
D
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
55.9
87
N.A.
80.9
81
N.A.
59.6
67.9
50.2
55.7
N.A.
N.A.
N.A.
23.6
32.1
Protein Similarity:
100
99.7
64.8
94
N.A.
89.8
89.8
N.A.
69.6
80.9
69.9
72.9
N.A.
N.A.
N.A.
44.3
53.8
P-Site Identity:
100
100
100
86.6
N.A.
80
86.6
N.A.
40
6.6
6.6
20
N.A.
N.A.
N.A.
20
20
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
66.6
13.3
40
40
N.A.
N.A.
N.A.
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
16
0
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
16
0
8
0
0
0
0
0
62
0
0
8
0
0
% D
% Glu:
8
54
8
0
16
16
8
8
0
8
16
0
54
8
24
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
0
8
0
16
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
54
0
0
0
0
16
47
% H
% Ile:
0
0
0
8
0
0
0
16
0
0
0
0
0
8
0
% I
% Lys:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
0
0
8
0
62
0
0
0
8
70
8
39
0
% L
% Met:
8
0
31
0
16
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
8
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% P
% Gln:
8
0
0
0
8
47
0
0
0
0
0
0
16
0
8
% Q
% Arg:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
8
62
0
8
8
47
8
0
0
0
0
8
8
% S
% Thr:
0
0
0
0
0
8
8
0
8
0
0
16
0
0
0
% T
% Val:
8
0
31
0
31
0
0
8
16
0
0
8
8
24
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _