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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A2 All Species: 25.76
Human Site: T449 Identified Species: 47.22
UniProt: P50443 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50443 NP_000103.2 739 81662 T449 K T L V K E S T G C H T Q L S
Chimpanzee Pan troglodytes XP_001164642 739 81648 T449 K T L V K E S T G C H T Q L S
Rhesus Macaque Macaca mulatta XP_001098562 860 94599 T570 K T L V K E S T G C Q T Q L S
Dog Lupus familis XP_855107 742 81873 T452 K T L V K E S T G C Q T Q L S
Cat Felis silvestris
Mouse Mus musculus Q62273 739 81586 T449 K T L V K E S T G C Q T Q L S
Rat Rattus norvegicus O70531 739 82010 T449 K T L V K E S T G C Q T Q L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506994 916 100035 T625 K T L V K E S T G C Q T Q V S
Chicken Gallus gallus XP_425183 712 78105 L441 S G I V T S L L I L I V L L V
Frog Xenopus laevis NP_001084442 719 79740 V442 S S V I S A I V V L L V L L F
Zebra Danio Brachydanio rerio XP_685114 699 76761 L428 V T A L V L L L V M L V I A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 L482 K F G E L K S L W P V F K I D
Sea Urchin Strong. purpuratus XP_793050 822 89984 G457 R S L L Q D L G G G K T Q I A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04722 677 74050 V406 V A I G F M N V L G S F T S C
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 55.9 87 N.A. 80.9 81 N.A. 59.6 67.9 50.2 55.7 N.A. N.A. N.A. 23.6 32.1
Protein Similarity: 100 99.7 64.8 94 N.A. 89.8 89.8 N.A. 69.6 80.9 69.9 72.9 N.A. N.A. N.A. 44.3 53.8
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 86.6 13.3 6.6 6.6 N.A. N.A. N.A. 13.3 26.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 93.3 20 26.6 13.3 N.A. N.A. N.A. 33.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 8 0 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 54 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 8 0 54 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 8 0 0 0 0 0 0 16 0 0 8 % F
% Gly: 0 8 8 8 0 0 0 8 62 16 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % H
% Ile: 0 0 16 8 0 0 8 0 8 0 8 0 8 16 0 % I
% Lys: 62 0 0 0 54 8 0 0 0 0 8 0 8 0 0 % K
% Leu: 0 0 62 16 8 8 24 24 8 16 16 0 16 62 0 % L
% Met: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 39 0 62 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 16 0 0 8 8 62 0 0 0 8 0 0 8 54 % S
% Thr: 0 62 0 0 8 0 0 54 0 0 0 62 8 0 0 % T
% Val: 16 0 8 62 8 0 0 16 16 0 8 24 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _