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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC26A2
All Species:
21.21
Human Site:
T627
Identified Species:
38.89
UniProt:
P50443
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50443
NP_000103.2
739
81662
T627
K
I
K
E
K
V
V
T
L
G
G
I
Q
D
E
Chimpanzee
Pan troglodytes
XP_001164642
739
81648
T627
K
I
K
E
K
V
V
T
L
G
G
I
Q
D
E
Rhesus Macaque
Macaca mulatta
XP_001098562
860
94599
T748
K
I
K
E
E
V
V
T
P
G
G
I
Q
D
E
Dog
Lupus familis
XP_855107
742
81873
I630
K
I
T
K
E
T
V
I
L
S
G
V
Q
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q62273
739
81586
T627
K
L
K
E
E
M
V
T
F
R
G
D
P
D
E
Rat
Rattus norvegicus
O70531
739
82010
T627
K
L
K
E
E
T
V
T
F
H
G
D
P
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506994
916
100035
T804
R
L
R
E
D
A
V
T
F
S
G
S
Q
E
K
Chicken
Gallus gallus
XP_425183
712
78105
R601
K
A
A
K
R
M
L
R
E
K
E
A
G
S
G
Frog
Xenopus laevis
NP_001084442
719
79740
Q603
M
E
K
K
A
K
N
Q
G
K
R
K
Q
V
D
Zebra Danio
Brachydanio rerio
XP_685114
699
76761
S588
K
Q
R
K
Q
K
H
S
R
E
D
Q
K
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94225
782
87457
F664
A
A
G
I
Q
C
F
F
V
V
Q
K
S
D
L
Sea Urchin
Strong. purpuratus
XP_793050
822
89984
T685
A
E
L
L
E
A
G
T
S
S
S
R
S
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04722
677
74050
L566
I
F
R
V
K
S
A
L
L
C
F
A
N
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
55.9
87
N.A.
80.9
81
N.A.
59.6
67.9
50.2
55.7
N.A.
N.A.
N.A.
23.6
32.1
Protein Similarity:
100
99.7
64.8
94
N.A.
89.8
89.8
N.A.
69.6
80.9
69.9
72.9
N.A.
N.A.
N.A.
44.3
53.8
P-Site Identity:
100
100
86.6
53.3
N.A.
53.3
53.3
N.A.
33.3
6.6
13.3
13.3
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
93.3
73.3
N.A.
73.3
66.6
N.A.
66.6
33.3
26.6
46.6
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
8
0
8
16
8
0
0
0
0
16
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
8
16
0
54
16
% D
% Glu:
0
16
0
47
39
0
0
0
8
8
8
0
0
8
54
% E
% Phe:
0
8
0
0
0
0
8
8
24
0
8
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
8
0
8
24
54
0
8
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
8
31
0
8
0
0
0
8
0
0
0
24
0
0
0
% I
% Lys:
62
0
47
31
24
16
0
0
0
16
0
16
8
0
8
% K
% Leu:
0
24
8
8
0
0
8
8
31
0
0
0
0
0
8
% L
% Met:
8
0
0
0
0
16
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
16
0
0
% P
% Gln:
0
8
0
0
16
0
0
8
0
0
8
8
47
8
0
% Q
% Arg:
8
0
24
0
8
0
0
8
8
8
8
8
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
8
8
24
8
8
16
8
8
% S
% Thr:
0
0
8
0
0
16
0
54
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
24
54
0
8
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _