Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A2 All Species: 15.76
Human Site: Y102 Identified Species: 28.89
UniProt: P50443 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50443 NP_000103.2 739 81662 Y102 V L Q W L P K Y D L K K N I L
Chimpanzee Pan troglodytes XP_001164642 739 81648 Y102 V L Q W L P K Y D L K K N I L
Rhesus Macaque Macaca mulatta XP_001098562 860 94599 L223 S S P S G I H L E L Q R E S S
Dog Lupus familis XP_855107 742 81873 D105 L R W L P K Y D L K K N I L G
Cat Felis silvestris
Mouse Mus musculus Q62273 739 81586 Y102 V L R W L P K Y D L K K N I L
Rat Rattus norvegicus O70531 739 82010 Y102 V L R W L P K Y D L K K N I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506994 916 100035 F278 Q W L P K Y K F K K Y I L G D
Chicken Gallus gallus XP_425183 712 78105 P96 I V G V L L V P Q S I A Y S L
Frog Xenopus laevis NP_001084442 719 79740 Q96 I G I I L V P Q A I A Y S L L
Zebra Danio Brachydanio rerio XP_685114 699 76761 S83 W I I G D A M S G L I V G I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 F101 Y T A I F P S F L Y I F F G T
Sea Urchin Strong. purpuratus XP_793050 822 89984 G109 G I F R I P H G M A H A I L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04722 677 74050 S61 L D C P E P P S P W H E L K R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 55.9 87 N.A. 80.9 81 N.A. 59.6 67.9 50.2 55.7 N.A. N.A. N.A. 23.6 32.1
Protein Similarity: 100 99.7 64.8 94 N.A. 89.8 89.8 N.A. 69.6 80.9 69.9 72.9 N.A. N.A. N.A. 44.3 53.8
P-Site Identity: 100 100 6.6 6.6 N.A. 93.3 93.3 N.A. 6.6 13.3 13.3 20 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 26.6 20 N.A. 100 100 N.A. 13.3 26.6 40 26.6 N.A. N.A. N.A. 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 0 0 8 8 8 16 0 0 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 0 0 8 31 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 8 0 0 0 8 0 0 8 8 0 0 % E
% Phe: 0 0 8 0 8 0 0 16 0 0 0 8 8 0 0 % F
% Gly: 8 8 8 8 8 0 0 8 8 0 0 0 8 16 8 % G
% His: 0 0 0 0 0 0 16 0 0 0 16 0 0 0 0 % H
% Ile: 16 16 16 16 8 8 0 0 0 8 24 8 16 39 0 % I
% Lys: 0 0 0 0 8 8 39 0 8 16 39 31 0 8 0 % K
% Leu: 16 31 8 8 47 8 0 8 16 47 0 0 16 24 54 % L
% Met: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 31 0 0 % N
% Pro: 0 0 8 16 8 54 16 8 8 0 0 0 0 0 0 % P
% Gln: 8 0 16 0 0 0 0 8 8 0 8 0 0 0 0 % Q
% Arg: 0 8 16 8 0 0 0 0 0 0 0 8 0 0 8 % R
% Ser: 8 8 0 8 0 0 8 16 0 8 0 0 8 16 8 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % T
% Val: 31 8 0 8 0 8 8 0 0 0 0 8 0 0 0 % V
% Trp: 8 8 8 31 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 8 31 0 8 8 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _