Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A2 All Species: 5.45
Human Site: Y185 Identified Species: 10
UniProt: P50443 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50443 NP_000103.2 739 81662 Y185 R E L Q K A G Y D N A H S A P
Chimpanzee Pan troglodytes XP_001164642 739 81648 Y185 R E L Q K A G Y D N A H S A P
Rhesus Macaque Macaca mulatta XP_001098562 860 94599 V306 K K N I L G D V M S G L I V G
Dog Lupus familis XP_855107 742 81873 D188 E L H K A G Y D T A D N A P S
Cat Felis silvestris
Mouse Mus musculus Q62273 739 81586 P185 R E L H K A C P D T D A T S S
Rat Rattus norvegicus O70531 739 82010 P185 R E L H K A C P D I D T T S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506994 916 100035 A361 V H R A G Y D A E Q A V R A A
Chicken Gallus gallus XP_425183 712 78105 A179 M H V N S T I A P V N Q T S Q
Frog Xenopus laevis NP_001084442 719 79740 S179 S D L N I T R S I N I S M G L
Zebra Danio Brachydanio rerio XP_685114 699 76761 V166 N Q T T L G N V D N S T G P I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 E184 F V E E V T M E M W T E G V T
Sea Urchin Strong. purpuratus XP_793050 822 89984 A192 S Y T V G S E A G F N S S I G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04722 677 74050 P144 A T L A K L D P Q Y G L Y T S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 55.9 87 N.A. 80.9 81 N.A. 59.6 67.9 50.2 55.7 N.A. N.A. N.A. 23.6 32.1
Protein Similarity: 100 99.7 64.8 94 N.A. 89.8 89.8 N.A. 69.6 80.9 69.9 72.9 N.A. N.A. N.A. 44.3 53.8
P-Site Identity: 100 100 0 0 N.A. 40 40 N.A. 13.3 0 13.3 13.3 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 100 20 20 N.A. 53.3 53.3 N.A. 20 20 20 26.6 N.A. N.A. N.A. 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 16 8 31 0 24 0 8 24 8 8 24 8 % A
% Cys: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 24 8 39 0 24 0 0 0 0 % D
% Glu: 8 31 8 8 0 0 8 8 8 0 0 8 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 16 24 16 0 8 0 16 0 16 8 16 % G
% His: 0 16 8 16 0 0 0 0 0 0 0 16 0 0 0 % H
% Ile: 0 0 0 8 8 0 8 0 8 8 8 0 8 8 8 % I
% Lys: 8 8 0 8 39 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 47 0 16 8 0 0 0 0 0 16 0 0 8 % L
% Met: 8 0 0 0 0 0 8 0 16 0 0 0 8 0 0 % M
% Asn: 8 0 8 16 0 0 8 0 0 31 16 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 24 8 0 0 0 0 16 16 % P
% Gln: 0 8 0 16 0 0 0 0 8 8 0 8 0 0 8 % Q
% Arg: 31 0 8 0 0 0 8 0 0 0 0 0 8 0 0 % R
% Ser: 16 0 0 0 8 8 0 8 0 8 8 16 24 24 31 % S
% Thr: 0 8 16 8 0 24 0 0 8 8 8 16 24 8 8 % T
% Val: 8 8 8 8 8 0 0 16 0 8 0 8 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 8 16 0 8 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _