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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC26A2
All Species:
23.64
Human Site:
Y271
Identified Species:
43.33
UniProt:
P50443
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50443
NP_000103.2
739
81662
Y271
I
L
T
S
Q
A
K
Y
L
L
G
L
N
L
P
Chimpanzee
Pan troglodytes
XP_001164642
739
81648
Y271
I
L
T
S
Q
A
K
Y
L
L
G
L
N
L
P
Rhesus Macaque
Macaca mulatta
XP_001098562
860
94599
S392
A
P
S
L
G
M
V
S
N
G
S
M
L
L
N
Dog
Lupus familis
XP_855107
742
81873
Y274
I
L
T
S
Q
A
K
Y
L
L
G
L
S
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q62273
739
81586
Y271
I
L
T
S
Q
A
K
Y
L
L
G
L
S
L
P
Rat
Rattus norvegicus
O70531
739
82010
Y271
I
L
T
S
Q
A
K
Y
L
L
G
L
S
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506994
916
100035
Y447
I
L
T
S
Q
A
K
Y
L
L
G
L
N
I
P
Chicken
Gallus gallus
XP_425183
712
78105
I265
S
S
G
V
G
S
L
I
T
T
W
I
N
I
F
Frog
Xenopus laevis
NP_001084442
719
79740
L265
R
S
P
G
I
G
M
L
V
T
T
W
Y
N
I
Zebra Danio
Brachydanio rerio
XP_685114
699
76761
W252
W
G
S
L
I
K
T
W
I
S
L
F
K
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94225
782
87457
L270
L
Y
Y
R
I
W
D
L
V
E
N
L
D
N
V
Sea Urchin
Strong. purpuratus
XP_793050
822
89984
K278
V
F
T
S
Q
F
N
K
L
F
G
V
P
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04722
677
74050
A230
V
D
F
L
S
H
A
A
I
V
G
F
M
G
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
55.9
87
N.A.
80.9
81
N.A.
59.6
67.9
50.2
55.7
N.A.
N.A.
N.A.
23.6
32.1
Protein Similarity:
100
99.7
64.8
94
N.A.
89.8
89.8
N.A.
69.6
80.9
69.9
72.9
N.A.
N.A.
N.A.
44.3
53.8
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
93.3
6.6
0
0
N.A.
N.A.
N.A.
6.6
40
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
26.6
6.6
20
N.A.
N.A.
N.A.
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
47
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
8
8
0
0
8
0
0
0
8
0
16
0
0
8
% F
% Gly:
0
8
8
8
16
8
0
0
0
8
62
0
0
8
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
47
0
0
0
24
0
0
8
16
0
0
8
0
16
8
% I
% Lys:
0
0
0
0
0
8
47
8
0
0
0
0
8
0
0
% K
% Leu:
8
47
0
24
0
0
8
16
54
47
8
54
8
47
8
% L
% Met:
0
0
0
0
0
8
8
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
8
0
8
0
31
24
8
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
54
% P
% Gln:
0
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
16
16
54
8
8
0
8
0
8
8
0
24
0
0
% S
% Thr:
0
0
54
0
0
0
8
0
8
16
8
0
0
0
0
% T
% Val:
16
0
0
8
0
0
8
0
16
8
0
8
0
8
8
% V
% Trp:
8
0
0
0
0
8
0
8
0
0
8
8
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
47
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _