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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC26A2
All Species:
26.06
Human Site:
Y356
Identified Species:
47.78
UniProt:
P50443
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50443
NP_000103.2
739
81662
Y356
F
G
K
L
H
E
N
Y
N
S
S
I
A
G
H
Chimpanzee
Pan troglodytes
XP_001164642
739
81648
Y356
F
G
K
L
H
E
N
Y
N
S
S
I
A
G
H
Rhesus Macaque
Macaca mulatta
XP_001098562
860
94599
Y477
F
G
K
L
H
E
N
Y
N
S
S
I
A
G
H
Dog
Lupus familis
XP_855107
742
81873
Y359
F
G
K
L
N
E
K
Y
N
T
S
I
A
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62273
739
81586
Y356
F
G
K
L
N
G
N
Y
N
S
S
I
A
G
H
Rat
Rattus norvegicus
O70531
739
82010
Y356
F
G
K
L
N
E
N
Y
N
S
S
I
A
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506994
916
100035
Y532
F
G
Q
L
K
E
K
Y
G
S
S
V
A
G
H
Chicken
Gallus gallus
XP_425183
712
78105
P348
H
I
P
T
G
F
L
P
P
S
P
P
E
W
N
Frog
Xenopus laevis
NP_001084442
719
79740
P349
V
I
P
T
G
F
I
P
P
Q
V
P
N
F
S
Zebra Danio
Brachydanio rerio
XP_685114
699
76761
S335
T
G
F
M
A
P
Q
S
P
N
L
S
L
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94225
782
87457
K389
V
E
K
R
Y
K
Y
K
I
N
H
G
Q
E
L
Sea Urchin
Strong. purpuratus
XP_793050
822
89984
G364
G
D
F
T
S
Q
F
G
M
P
I
V
G
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04722
677
74050
P313
F
W
L
P
A
I
A
P
L
I
A
V
V
V
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
55.9
87
N.A.
80.9
81
N.A.
59.6
67.9
50.2
55.7
N.A.
N.A.
N.A.
23.6
32.1
Protein Similarity:
100
99.7
64.8
94
N.A.
89.8
89.8
N.A.
69.6
80.9
69.9
72.9
N.A.
N.A.
N.A.
44.3
53.8
P-Site Identity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
66.6
6.6
0
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
80
13.3
0
20
N.A.
N.A.
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
8
0
0
0
8
0
54
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
47
0
0
0
0
0
0
8
16
0
% E
% Phe:
62
0
16
0
0
16
8
0
0
0
0
0
0
8
0
% F
% Gly:
8
62
0
0
16
8
0
8
8
0
0
8
8
54
0
% G
% His:
8
0
0
0
24
0
0
0
0
0
8
0
0
0
39
% H
% Ile:
0
16
0
0
0
8
8
0
8
8
8
47
0
0
8
% I
% Lys:
0
0
54
0
8
8
16
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
54
0
0
8
0
8
0
8
0
8
0
8
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
24
0
39
0
47
16
0
0
8
0
8
% N
% Pro:
0
0
16
8
0
8
0
24
24
8
8
16
0
0
8
% P
% Gln:
0
0
8
0
0
8
8
0
0
8
0
0
8
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
8
0
54
54
8
0
0
24
% S
% Thr:
8
0
0
24
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
16
0
0
0
0
0
0
0
0
0
8
24
8
16
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
8
0
8
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _