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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A2 All Species: 7.27
Human Site: Y51 Identified Species: 13.33
UniProt: P50443 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50443 NP_000103.2 739 81662 Y51 T N D Q C R P Y H R I L I E R
Chimpanzee Pan troglodytes XP_001164642 739 81648 Y51 T N D Q C R P Y H R I L I E R
Rhesus Macaque Macaca mulatta XP_001098562 860 94599 V82 Q I A R R R V V R G R H P P R
Dog Lupus familis XP_855107 742 81873 Y53 A N D Q C T L Y R R I H M E P
Cat Felis silvestris
Mouse Mus musculus Q62273 739 81586 F51 T G H G R R A F R R I H M E L
Rat Rattus norvegicus O70531 739 82010 F51 P S D R R R A F R R I H M E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506994 916 100035 H225 G S D Q W C L H P R I L L E P
Chicken Gallus gallus XP_425183 712 78105 C52 Q V K K T C S C T P A K V K D
Frog Xenopus laevis NP_001084442 719 79740 N52 V K K Q C T C N S K Q L K K T
Zebra Danio Brachydanio rerio XP_685114 699 76761 L40 K V S W K E A L R K K V K K C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 K53 P I I T W L P K Y D W S H S F
Sea Urchin Strong. purpuratus XP_793050 822 89984 R56 T L L T R L R R K A G K C S C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04722 677 74050 P18 S L S H Q V L P N T S N S T H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 55.9 87 N.A. 80.9 81 N.A. 59.6 67.9 50.2 55.7 N.A. N.A. N.A. 23.6 32.1
Protein Similarity: 100 99.7 64.8 94 N.A. 89.8 89.8 N.A. 69.6 80.9 69.9 72.9 N.A. N.A. N.A. 44.3 53.8
P-Site Identity: 100 100 13.3 53.3 N.A. 33.3 33.3 N.A. 40 0 20 0 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 20 60 N.A. 46.6 60 N.A. 60 20 33.3 20 N.A. N.A. N.A. 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 0 24 0 0 8 8 0 0 0 0 % A
% Cys: 0 0 0 0 31 16 8 8 0 0 0 0 8 0 16 % C
% Asp: 0 0 39 0 0 0 0 0 0 8 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 0 0 47 0 % E
% Phe: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 8 % F
% Gly: 8 8 0 8 0 0 0 0 0 8 8 0 0 0 0 % G
% His: 0 0 8 8 0 0 0 8 16 0 0 31 8 0 8 % H
% Ile: 0 16 8 0 0 0 0 0 0 0 47 0 16 0 0 % I
% Lys: 8 8 16 8 8 0 0 8 8 16 8 16 16 24 0 % K
% Leu: 0 16 8 0 0 16 24 8 0 0 0 31 8 0 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 % M
% Asn: 0 24 0 0 0 0 0 8 8 0 0 8 0 0 0 % N
% Pro: 16 0 0 0 0 0 24 8 8 8 0 0 8 8 16 % P
% Gln: 16 0 0 39 8 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 16 31 39 8 8 39 47 8 0 0 0 24 % R
% Ser: 8 16 16 0 0 0 8 0 8 0 8 8 8 16 0 % S
% Thr: 31 0 0 16 8 16 0 0 8 8 0 0 0 8 8 % T
% Val: 8 16 0 0 0 8 8 8 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 8 16 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 24 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _