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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB8
All Species:
10.61
Human Site:
S262
Identified Species:
29.17
UniProt:
P50452
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50452
NP_002631.3
374
42767
S262
N
S
E
K
L
T
K
S
K
V
Q
V
F
L
P
Chimpanzee
Pan troglodytes
XP_512167
488
55435
S376
N
S
E
K
L
T
K
S
K
V
Q
V
F
L
P
Rhesus Macaque
Macaca mulatta
XP_001093135
340
38810
S242
P
R
L
K
L
E
E
S
Y
D
L
E
P
F
L
Dog
Lupus familis
XP_848751
374
42380
N262
D
P
E
N
M
T
K
N
K
V
Q
V
F
L
P
Cat
Felis silvestris
Mouse
Mus musculus
O08800
374
42132
S262
N
P
E
T
L
T
E
S
Q
V
Q
V
F
L
P
Rat
Rattus norvegicus
Q4G075
379
42708
E262
L
R
E
W
T
K
R
E
N
L
E
N
I
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505689
375
42423
S262
T
N
P
D
M
M
D
S
T
E
V
E
V
F
L
Chicken
Gallus gallus
O73790
410
47365
K290
L
S
E
W
A
D
S
K
M
M
T
E
T
L
V
Frog
Xenopus laevis
Q52L45
377
42679
M263
I
H
E
W
T
E
N
M
M
P
T
D
V
H
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76
87.6
83.4
N.A.
78.3
51.1
N.A.
60.7
40.4
50.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
76.4
89.5
92.2
N.A.
88.7
66.4
N.A.
78.9
60.7
67.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
66.6
N.A.
73.3
6.6
N.A.
6.6
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
86.6
N.A.
86.6
26.6
N.A.
20
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
12
0
12
12
0
0
12
0
12
0
12
0
% D
% Glu:
0
0
78
0
0
23
23
12
0
12
12
34
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
45
23
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% I
% Lys:
0
0
0
34
0
12
34
12
34
0
0
0
0
0
0
% K
% Leu:
23
0
12
0
45
0
0
0
0
12
12
0
0
56
23
% L
% Met:
0
0
0
0
23
12
0
12
23
12
0
0
0
0
0
% M
% Asn:
34
12
0
12
0
0
12
12
12
0
0
12
0
0
0
% N
% Pro:
12
23
12
0
0
0
0
0
0
12
0
0
12
0
45
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
45
0
0
0
0
% Q
% Arg:
0
23
0
0
0
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
0
34
0
0
0
0
12
56
0
0
0
0
0
0
0
% S
% Thr:
12
0
0
12
23
45
0
0
12
0
23
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
45
12
45
23
0
23
% V
% Trp:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _