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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SERPINB8 All Species: 8.79
Human Site: T187 Identified Species: 24.17
UniProt: P50452 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50452 NP_002631.3 374 42767 T187 T R G M L F K T N E E K K T V
Chimpanzee Pan troglodytes XP_512167 488 55435 T301 T R G M L F K T N E E K K T V
Rhesus Macaque Macaca mulatta XP_001093135 340 38810 A167 V Q M M F K E A K F K M G Y V
Dog Lupus familis XP_848751 374 42380 I187 T R G M P F K I N Q E R K T V
Cat Felis silvestris
Mouse Mus musculus O08800 374 42132 T187 T R G M P F K T N Q E K K T V
Rat Rattus norvegicus Q4G075 379 42708 L187 T T D A P F R L N K K N T K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505689 375 42423 I187 T R E R A F K I S K S K E K P
Chicken Gallus gallus O73790 410 47365 L215 T S I Q P F R L S K N K S K P
Frog Xenopus laevis Q52L45 377 42679 L188 T T D M P F Q L N K K E Q K T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76 87.6 83.4 N.A. 78.3 51.1 N.A. 60.7 40.4 50.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 76.4 89.5 92.2 N.A. 88.7 66.4 N.A. 78.9 60.7 67.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 73.3 N.A. 86.6 20 N.A. 33.3 20 26.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 86.6 N.A. 93.3 40 N.A. 53.3 40 60 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 12 0 0 12 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 23 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 12 0 0 0 12 0 0 23 45 12 12 0 0 % E
% Phe: 0 0 0 0 12 89 0 0 0 12 0 0 0 0 0 % F
% Gly: 0 0 45 0 0 0 0 0 0 0 0 0 12 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 23 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 12 56 0 12 45 34 56 45 45 0 % K
% Leu: 0 0 0 0 23 0 0 34 0 0 0 0 0 0 0 % L
% Met: 0 0 12 67 0 0 0 0 0 0 0 12 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 67 0 12 12 0 0 0 % N
% Pro: 0 0 0 0 56 0 0 0 0 0 0 0 0 0 23 % P
% Gln: 0 12 0 12 0 0 12 0 0 23 0 0 12 0 0 % Q
% Arg: 0 56 0 12 0 0 23 0 0 0 0 12 0 0 0 % R
% Ser: 0 12 0 0 0 0 0 0 23 0 12 0 12 0 12 % S
% Thr: 89 23 0 0 0 0 0 34 0 0 0 0 12 45 12 % T
% Val: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 56 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _