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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINH1
All Species:
19.39
Human Site:
S138
Identified Species:
47.41
UniProt:
P50454
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50454
NP_001226.2
418
46441
S138
G
S
R
L
Y
G
P
S
S
V
S
F
A
D
D
Chimpanzee
Pan troglodytes
XP_001175002
408
45396
S128
G
S
R
L
Y
G
P
S
S
V
S
F
A
D
D
Rhesus Macaque
Macaca mulatta
XP_001084827
582
63652
S302
G
S
R
L
Y
G
P
S
S
V
S
F
A
D
D
Dog
Lupus familis
XP_541071
397
44956
G135
E
D
M
K
A
Y
F
G
A
E
P
Q
S
V
N
Cat
Felis silvestris
Mouse
Mus musculus
P19324
417
46571
S137
G
S
R
L
Y
G
P
S
S
V
S
F
A
D
D
Rat
Rattus norvegicus
P29457
417
46499
S137
G
S
R
L
Y
G
P
S
S
V
S
F
A
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521822
354
39342
T116
I
N
E
W
A
A
Q
T
T
G
G
K
L
P
E
Chicken
Gallus gallus
P13731
405
45664
A125
G
N
R
L
Y
G
P
A
S
I
N
F
A
D
D
Frog
Xenopus laevis
Q52L45
377
42679
A125
G
T
V
D
F
I
S
A
L
E
D
A
R
K
E
Zebra Danio
Brachydanio rerio
NP_001103844
403
44955
L132
V
S
F
V
D
D
F
L
K
S
S
K
K
H
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
71.1
27.5
N.A.
94.2
94.5
N.A.
72.4
76.7
28.7
65.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.6
71.1
48
N.A.
96.1
96.1
N.A.
78.2
88.5
49.5
83.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
73.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
26.6
100
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
10
0
20
10
0
0
10
60
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
10
10
0
0
0
0
10
0
0
60
60
% D
% Glu:
10
0
10
0
0
0
0
0
0
20
0
0
0
0
20
% E
% Phe:
0
0
10
0
10
0
20
0
0
0
0
60
0
0
0
% F
% Gly:
70
0
0
0
0
60
0
10
0
10
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
0
0
20
10
10
0
% K
% Leu:
0
0
0
60
0
0
0
10
10
0
0
0
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
0
0
0
0
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
60
0
0
0
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
60
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
60
0
0
0
0
10
50
60
10
60
0
10
0
0
% S
% Thr:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% T
% Val:
10
0
10
10
0
0
0
0
0
50
0
0
0
10
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
60
10
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _