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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX2
All Species:
18.79
Human Site:
S245
Identified Species:
34.44
UniProt:
P50458
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50458
NP_004780.3
406
44373
S245
A
A
Y
N
A
A
L
S
C
N
E
N
D
A
E
Chimpanzee
Pan troglodytes
XP_528427
365
39945
Y219
H
L
D
R
D
Q
P
Y
P
S
S
Q
K
T
K
Rhesus Macaque
Macaca mulatta
XP_001083699
406
44385
S245
A
A
Y
N
A
A
L
S
C
N
E
N
D
A
E
Dog
Lupus familis
XP_548461
406
44339
S245
A
A
Y
N
A
A
L
S
C
N
E
N
D
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S2
406
44401
S245
A
A
Y
N
A
A
L
S
C
N
E
N
D
A
E
Rat
Rattus norvegicus
P36198
426
47400
S243
A
A
Y
N
A
A
L
S
C
N
E
N
D
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90881
397
44091
N249
Y
N
S
G
C
N
E
N
E
A
D
H
M
D
R
Frog
Xenopus laevis
Q68EY3
331
37417
R185
K
E
N
L
V
Y
C
R
I
H
F
E
L
L
V
Zebra Danio
Brachydanio rerio
Q1LWV4
396
44002
N249
Y
S
S
G
C
N
E
N
D
A
D
H
L
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29673
469
52035
R268
R
T
H
Y
S
I
A
R
E
G
D
T
A
S
S
Honey Bee
Apis mellifera
XP_392622
558
60939
A412
K
D
L
E
A
M
T
A
N
I
D
L
N
A
D
Nematode Worm
Caenorhab. elegans
P20154
405
45759
L253
T
T
I
K
A
K
Q
L
E
T
L
K
N
A
F
Sea Urchin
Strong. purpuratus
XP_782032
474
51738
H261
D
P
C
D
P
M
G
H
H
G
H
H
P
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
99.7
99.5
N.A.
99
86.6
N.A.
N.A.
70.6
55.1
71.4
N.A.
39.4
36
22.6
39.2
Protein Similarity:
100
89.9
99.7
99.7
N.A.
99.7
88.9
N.A.
N.A.
80.7
64.7
81.7
N.A.
53.5
45.8
40.3
55
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
0
0
0
N.A.
0
13.3
13.3
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
20
6.6
26.6
N.A.
26.6
40
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
39
0
0
54
39
8
8
0
16
0
0
8
54
0
% A
% Cys:
0
0
8
0
16
0
8
0
39
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
8
0
0
0
8
0
31
0
39
16
8
% D
% Glu:
0
8
0
8
0
0
16
0
24
0
39
8
0
0
39
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
0
0
0
16
0
0
8
0
0
16
0
0
0
8
0
% G
% His:
8
0
8
0
0
0
0
8
8
8
8
24
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
8
8
0
0
0
0
0
% I
% Lys:
16
0
0
8
0
8
0
0
0
0
0
8
8
0
8
% K
% Leu:
0
8
8
8
0
0
39
8
0
0
8
8
16
8
8
% L
% Met:
0
0
0
0
0
16
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
8
39
0
16
0
16
8
39
0
39
16
0
0
% N
% Pro:
0
8
0
0
8
0
8
0
8
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% Q
% Arg:
8
0
0
8
0
0
0
16
0
0
0
0
0
0
16
% R
% Ser:
0
8
16
0
8
0
0
39
0
8
8
0
0
8
8
% S
% Thr:
8
16
0
0
0
0
8
0
0
8
0
8
0
8
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
39
8
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _