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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX2
All Species:
18.48
Human Site:
S336
Identified Species:
33.89
UniProt:
P50458
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50458
NP_004780.3
406
44373
S336
E
N
T
G
V
D
K
S
T
D
A
A
L
Q
T
Chimpanzee
Pan troglodytes
XP_528427
365
39945
T296
N
T
G
V
D
K
S
T
D
A
A
L
Q
T
G
Rhesus Macaque
Macaca mulatta
XP_001083699
406
44385
S336
E
N
T
G
V
D
K
S
T
D
T
A
L
Q
T
Dog
Lupus familis
XP_548461
406
44339
S336
E
N
T
G
V
D
K
S
T
E
A
A
L
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S2
406
44401
T336
E
N
T
G
V
D
K
T
S
D
A
T
L
Q
T
Rat
Rattus norvegicus
P36198
426
47400
T334
E
N
T
G
V
D
K
T
S
D
A
T
L
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90881
397
44091
L327
A
K
F
R
R
N
L
L
R
Q
E
N
G
G
V
Frog
Xenopus laevis
Q68EY3
331
37417
Y262
D
L
D
R
D
Q
T
Y
P
P
S
Q
K
T
K
Zebra Danio
Brachydanio rerio
Q1LWV4
396
44002
L327
A
K
F
R
R
N
V
L
R
Q
E
N
G
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29673
469
52035
G358
E
Y
V
D
F
G
R
G
S
H
L
S
S
S
S
Honey Bee
Apis mellifera
XP_392622
558
60939
W489
P
K
R
V
L
Q
V
W
F
Q
N
A
R
A
K
Nematode Worm
Caenorhab. elegans
P20154
405
45759
P332
D
Q
Q
F
Y
P
P
P
P
P
S
N
V
Q
F
Sea Urchin
Strong. purpuratus
XP_782032
474
51738
A353
D
E
K
S
E
K
N
A
S
E
C
D
G
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
99.7
99.5
N.A.
99
86.6
N.A.
N.A.
70.6
55.1
71.4
N.A.
39.4
36
22.6
39.2
Protein Similarity:
100
89.9
99.7
99.7
N.A.
99.7
88.9
N.A.
N.A.
80.7
64.7
81.7
N.A.
53.5
45.8
40.3
55
P-Site Identity:
100
6.6
93.3
93.3
N.A.
80
80
N.A.
N.A.
0
0
0
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
13.3
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
6.6
13.3
6.6
N.A.
33.3
13.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
0
8
0
8
39
31
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
24
0
8
8
16
39
0
0
8
31
0
8
0
8
0
% D
% Glu:
47
8
0
0
8
0
0
0
0
16
16
0
0
0
0
% E
% Phe:
0
0
16
8
8
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
8
39
0
8
0
8
0
0
0
0
24
16
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
24
8
0
0
16
39
0
0
0
0
0
8
0
16
% K
% Leu:
0
8
0
0
8
0
8
16
0
0
8
8
39
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
39
0
0
0
16
8
0
0
0
8
24
0
0
0
% N
% Pro:
8
0
0
0
0
8
8
8
16
16
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
16
0
0
0
24
0
8
8
47
8
% Q
% Arg:
0
0
8
24
16
0
8
0
16
0
0
0
8
0
0
% R
% Ser:
0
0
0
8
0
0
8
24
31
0
16
8
8
8
8
% S
% Thr:
0
8
39
0
0
0
8
24
24
0
8
16
0
16
39
% T
% Val:
0
0
8
16
39
0
16
0
0
0
0
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _