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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX2
All Species:
21.52
Human Site:
S357
Identified Species:
39.44
UniProt:
P50458
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50458
NP_004780.3
406
44373
S357
A
S
E
L
S
N
A
S
L
S
P
S
S
T
P
Chimpanzee
Pan troglodytes
XP_528427
365
39945
L317
S
E
L
S
N
A
S
L
S
P
S
S
T
P
T
Rhesus Macaque
Macaca mulatta
XP_001083699
406
44385
S357
A
S
E
L
S
N
A
S
L
S
P
S
S
T
P
Dog
Lupus familis
XP_548461
406
44339
S357
A
S
E
L
S
N
A
S
L
S
P
S
S
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S2
406
44401
S357
A
S
E
L
S
N
A
S
L
S
P
S
S
T
P
Rat
Rattus norvegicus
P36198
426
47400
S355
A
S
E
L
S
N
A
S
L
S
P
S
S
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90881
397
44091
A348
S
L
P
A
P
P
S
A
D
S
G
A
L
T
P
Frog
Xenopus laevis
Q68EY3
331
37417
M283
K
H
H
Q
L
R
T
M
K
S
Y
F
A
I
N
Zebra Danio
Brachydanio rerio
Q1LWV4
396
44002
D348
S
L
P
P
P
S
S
D
S
G
A
L
T
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29673
469
52035
L379
T
S
F
K
H
H
Q
L
R
T
M
K
S
Y
F
Honey Bee
Apis mellifera
XP_392622
558
60939
K510
K
Q
E
G
K
S
D
K
C
D
G
S
V
D
S
Nematode Worm
Caenorhab. elegans
P20154
405
45759
T353
T
S
P
N
N
P
E
T
I
Q
M
A
P
Q
F
Sea Urchin
Strong. purpuratus
XP_782032
474
51738
S374
V
D
D
Q
D
N
I
S
I
T
S
S
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
99.7
99.5
N.A.
99
86.6
N.A.
N.A.
70.6
55.1
71.4
N.A.
39.4
36
22.6
39.2
Protein Similarity:
100
89.9
99.7
99.7
N.A.
99.7
88.9
N.A.
N.A.
80.7
64.7
81.7
N.A.
53.5
45.8
40.3
55
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
20
6.6
6.6
N.A.
13.3
13.3
6.6
20
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
N.A.
46.6
13.3
33.3
N.A.
26.6
20
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
8
0
8
39
8
0
0
8
16
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
0
8
8
8
8
0
0
0
8
0
% D
% Glu:
0
8
47
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
16
% F
% Gly:
0
0
0
8
0
0
0
0
0
8
16
0
8
8
8
% G
% His:
0
8
8
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
16
0
0
0
0
8
0
% I
% Lys:
16
0
0
8
8
0
0
8
8
0
0
8
0
0
0
% K
% Leu:
0
16
8
39
8
0
0
16
39
0
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
16
0
0
0
0
% M
% Asn:
0
0
0
8
16
47
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
24
8
16
16
0
0
0
8
39
0
8
16
54
% P
% Gln:
0
8
0
16
0
0
8
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% R
% Ser:
24
54
0
8
39
16
24
47
16
54
16
62
47
0
8
% S
% Thr:
16
0
0
0
0
0
8
8
0
16
0
0
16
47
8
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _