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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX2
All Species:
21.52
Human Site:
T368
Identified Species:
39.44
UniProt:
P50458
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50458
NP_004780.3
406
44373
T368
S
S
T
P
T
T
L
T
D
L
T
S
P
T
L
Chimpanzee
Pan troglodytes
XP_528427
365
39945
D328
S
T
P
T
T
L
T
D
L
T
S
P
T
L
P
Rhesus Macaque
Macaca mulatta
XP_001083699
406
44385
T368
S
S
T
P
T
T
L
T
D
L
T
S
P
T
L
Dog
Lupus familis
XP_548461
406
44339
T368
S
S
T
P
T
T
L
T
D
L
T
S
P
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S2
406
44401
T368
S
S
T
P
T
T
L
T
D
L
T
S
P
T
L
Rat
Rattus norvegicus
P36198
426
47400
T366
S
S
T
P
T
T
L
T
D
L
T
S
P
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90881
397
44091
A359
A
L
T
P
P
G
T
A
T
T
L
T
D
L
T
Frog
Xenopus laevis
Q68EY3
331
37417
D294
F
A
I
N
H
N
P
D
A
K
D
L
K
Q
L
Zebra Danio
Brachydanio rerio
Q1LWV4
396
44002
T359
L
T
P
P
S
T
A
T
T
L
T
D
L
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29673
469
52035
H390
K
S
Y
F
A
I
N
H
N
P
D
A
K
D
L
Honey Bee
Apis mellifera
XP_392622
558
60939
G521
S
V
D
S
G
S
L
G
D
L
E
L
Y
G
N
Nematode Worm
Caenorhab. elegans
P20154
405
45759
T364
A
P
Q
F
A
V
P
T
E
N
M
N
M
V
P
Sea Urchin
Strong. purpuratus
XP_782032
474
51738
G385
S
G
G
G
G
G
S
G
S
G
S
D
P
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
99.7
99.5
N.A.
99
86.6
N.A.
N.A.
70.6
55.1
71.4
N.A.
39.4
36
22.6
39.2
Protein Similarity:
100
89.9
99.7
99.7
N.A.
99.7
88.9
N.A.
N.A.
80.7
64.7
81.7
N.A.
53.5
45.8
40.3
55
P-Site Identity:
100
13.3
100
93.3
N.A.
100
100
N.A.
N.A.
13.3
6.6
40
N.A.
13.3
26.6
6.6
20
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
100
N.A.
N.A.
26.6
13.3
53.3
N.A.
26.6
33.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
16
0
8
8
8
0
0
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
16
47
0
16
16
8
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% E
% Phe:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
8
16
16
0
16
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
8
0
0
16
0
0
% K
% Leu:
8
8
0
0
0
8
47
0
8
54
8
16
8
16
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
8
0
8
8
0
8
8
0
8
0
0
16
% N
% Pro:
0
8
16
54
8
0
16
0
0
8
0
8
47
0
16
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
62
47
0
8
8
8
8
0
8
0
16
39
0
0
0
% S
% Thr:
0
16
47
8
47
47
16
54
16
16
47
8
8
47
8
% T
% Val:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _