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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX2
All Species:
17.58
Human Site:
Y214
Identified Species:
32.22
UniProt:
P50458
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50458
NP_004780.3
406
44373
Y214
N
P
L
G
L
P
Y
Y
N
G
V
G
T
V
Q
Chimpanzee
Pan troglodytes
XP_528427
365
39945
K188
K
G
R
P
R
K
R
K
S
P
G
P
G
A
D
Rhesus Macaque
Macaca mulatta
XP_001083699
406
44385
Y214
N
P
L
G
L
P
Y
Y
N
G
V
G
T
V
Q
Dog
Lupus familis
XP_548461
406
44339
Y214
N
P
L
G
L
P
Y
Y
N
G
V
G
T
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S2
406
44401
Y214
N
P
L
G
L
P
Y
Y
N
G
V
G
T
V
Q
Rat
Rattus norvegicus
P36198
426
47400
Y212
L
T
L
G
L
P
Y
Y
N
G
V
G
T
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90881
397
44091
G218
L
A
L
P
Y
F
N
G
T
G
T
V
Q
K
G
Frog
Xenopus laevis
Q68EY3
331
37417
V154
V
M
R
A
R
E
S
V
Y
H
L
S
C
F
T
Zebra Danio
Brachydanio rerio
Q1LWV4
396
44002
G218
L
A
L
P
Y
F
N
G
T
G
T
V
Q
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29673
469
52035
C237
V
F
H
V
N
C
F
C
C
T
V
C
H
T
P
Honey Bee
Apis mellifera
XP_392622
558
60939
V381
D
A
G
S
P
P
K
V
P
Y
F
N
G
A
A
Nematode Worm
Caenorhab. elegans
P20154
405
45759
D222
A
C
D
E
V
G
L
D
D
G
E
G
D
C
G
Sea Urchin
Strong. purpuratus
XP_782032
474
51738
P230
F
F
Q
N
G
L
S
P
I
H
K
G
R
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
99.7
99.5
N.A.
99
86.6
N.A.
N.A.
70.6
55.1
71.4
N.A.
39.4
36
22.6
39.2
Protein Similarity:
100
89.9
99.7
99.7
N.A.
99.7
88.9
N.A.
N.A.
80.7
64.7
81.7
N.A.
53.5
45.8
40.3
55
P-Site Identity:
100
0
100
100
N.A.
100
86.6
N.A.
N.A.
13.3
0
13.3
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
86.6
N.A.
N.A.
13.3
6.6
13.3
N.A.
13.3
13.3
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
0
8
0
0
0
0
0
0
0
0
0
16
8
% A
% Cys:
0
8
0
0
0
8
0
8
8
0
0
8
8
8
0
% C
% Asp:
8
0
8
0
0
0
0
8
8
0
0
0
8
0
8
% D
% Glu:
0
0
0
8
0
8
0
0
0
0
8
0
0
0
0
% E
% Phe:
8
16
0
0
0
16
8
0
0
0
8
0
0
8
0
% F
% Gly:
0
8
8
39
8
8
0
16
0
62
8
54
16
0
24
% G
% His:
0
0
8
0
0
0
0
0
0
16
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
8
8
8
0
0
8
0
0
16
0
% K
% Leu:
24
0
54
0
39
8
8
0
0
0
8
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
31
0
0
8
8
0
16
0
39
0
0
8
0
0
0
% N
% Pro:
0
31
0
24
8
47
0
8
8
8
0
8
0
8
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
16
0
39
% Q
% Arg:
0
0
16
0
16
0
8
0
0
0
0
0
8
0
8
% R
% Ser:
0
0
0
8
0
0
16
0
8
0
0
8
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
16
8
16
0
39
8
8
% T
% Val:
16
0
0
8
8
0
0
16
0
0
47
16
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
39
39
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _