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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX2
All Species:
30.61
Human Site:
Y64
Identified Species:
56.11
UniProt:
P50458
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50458
NP_004780.3
406
44373
Y64
G
G
K
I
S
D
R
Y
Y
L
L
A
V
D
K
Chimpanzee
Pan troglodytes
XP_528427
365
39945
F53
L
E
S
E
L
T
C
F
S
K
D
G
S
I
Y
Rhesus Macaque
Macaca mulatta
XP_001083699
406
44385
Y64
G
G
K
I
S
D
R
Y
Y
L
L
A
V
D
K
Dog
Lupus familis
XP_548461
406
44339
Y64
G
G
K
I
S
D
R
Y
Y
L
L
A
V
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S2
406
44401
Y64
G
G
K
I
S
D
R
Y
Y
L
L
A
V
D
K
Rat
Rattus norvegicus
P36198
426
47400
Y63
G
G
K
I
S
D
R
Y
Y
L
L
A
V
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90881
397
44091
Y82
G
G
K
I
S
D
R
Y
Y
L
L
A
V
D
K
Frog
Xenopus laevis
Q68EY3
331
37417
A19
A
Y
P
F
R
P
A
A
A
M
L
F
H
G
I
Zebra Danio
Brachydanio rerio
Q1LWV4
396
44002
Y82
G
G
K
I
S
D
R
Y
Y
L
L
A
V
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29673
469
52035
S84
Y
G
T
E
S
F
R
S
Y
E
T
A
D
R
A
Honey Bee
Apis mellifera
XP_392622
558
60939
F229
G
L
R
I
S
D
R
F
Y
L
Q
A
V
D
R
Nematode Worm
Caenorhab. elegans
P20154
405
45759
Y79
A
Q
P
I
L
D
R
Y
V
F
T
V
L
G
K
Sea Urchin
Strong. purpuratus
XP_782032
474
51738
F65
G
G
R
I
C
D
R
F
Y
L
L
A
A
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
99.7
99.5
N.A.
99
86.6
N.A.
N.A.
70.6
55.1
71.4
N.A.
39.4
36
22.6
39.2
Protein Similarity:
100
89.9
99.7
99.7
N.A.
99.7
88.9
N.A.
N.A.
80.7
64.7
81.7
N.A.
53.5
45.8
40.3
55
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
100
6.6
100
N.A.
33.3
66.6
33.3
66.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
100
13.3
100
N.A.
33.3
86.6
40
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
8
8
8
0
0
77
8
0
8
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
77
0
0
0
0
8
0
8
70
0
% D
% Glu:
0
8
0
16
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
8
0
24
0
8
0
8
0
0
0
% F
% Gly:
70
70
0
0
0
0
0
0
0
0
0
8
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
77
0
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
54
0
0
0
0
0
0
8
0
0
0
0
62
% K
% Leu:
8
8
0
0
16
0
0
0
0
70
70
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
16
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
16
0
8
0
85
0
0
0
0
0
0
8
16
% R
% Ser:
0
0
8
0
70
0
0
8
8
0
0
0
8
0
0
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
16
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
8
62
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
62
77
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _