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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ST13
All Species:
26.67
Human Site:
S274
Identified Species:
45.13
UniProt:
P50502
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50502
NP_003923.2
369
41332
S274
E
E
E
A
R
R
Q
S
G
A
Q
Y
G
S
F
Chimpanzee
Pan troglodytes
XP_001141005
369
41277
S274
E
E
E
A
R
R
Q
S
G
A
Q
Y
G
S
F
Rhesus Macaque
Macaca mulatta
XP_001102391
369
41316
S274
E
E
E
A
R
R
Q
S
G
A
Q
Y
G
S
F
Dog
Lupus familis
XP_851691
369
41409
S274
E
E
E
A
R
R
Q
S
G
A
Q
Y
G
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q99L47
371
41637
S273
E
E
E
A
R
R
Q
S
G
S
Q
Y
G
S
F
Rat
Rattus norvegicus
P50503
368
41261
S273
E
E
E
A
R
R
Q
S
G
S
Q
F
G
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLF0
361
40140
G273
E
E
A
R
R
Q
A
G
G
A
Q
F
G
G
F
Frog
Xenopus laevis
NP_001086657
376
41338
A272
E
E
E
A
R
H
Q
A
G
A
Q
F
G
G
F
Zebra Danio
Brachydanio rerio
NP_956063
362
39842
G278
E
E
A
R
Q
Q
A
G
G
G
G
G
G
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
C4NYP8
377
41018
S280
Q
E
K
H
N
A
S
S
G
G
S
S
G
E
F
Honey Bee
Apis mellifera
XP_394645
378
42459
A261
R
Q
E
R
L
R
K
A
R
E
S
A
K
I
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196240
526
55041
K327
K
A
Q
E
E
R
R
K
R
E
A
E
E
G
F
Poplar Tree
Populus trichocarpa
XP_002303525
410
44622
P289
Q
S
S
S
S
R
K
P
G
G
M
P
S
G
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93YR3
441
46603
S286
K
E
E
Q
S
S
S
S
R
P
S
G
G
G
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.7
99.1
94
N.A.
93.8
92.1
N.A.
N.A.
80.2
74.1
69.9
N.A.
35.5
35.1
N.A.
39.5
Protein Similarity:
100
95.6
99.7
96.4
N.A.
96.7
96.4
N.A.
N.A.
88.6
85.3
80.4
N.A.
53.3
55
N.A.
52.8
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
N.A.
53.3
73.3
26.6
N.A.
33.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
66.6
86.6
46.6
N.A.
46.6
40
N.A.
33.3
Percent
Protein Identity:
46.5
N.A.
N.A.
43.3
N.A.
N.A.
Protein Similarity:
66.8
N.A.
N.A.
60.7
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
50
0
8
15
15
0
43
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
65
79
65
8
8
0
0
0
0
15
0
8
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
22
0
0
86
% F
% Gly:
0
0
0
0
0
0
0
15
79
22
8
15
79
36
8
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
15
0
8
0
0
0
15
8
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
8
0
8
0
0
0
% P
% Gln:
15
8
8
8
8
15
50
0
0
0
58
0
0
0
0
% Q
% Arg:
8
0
0
22
58
65
8
0
22
0
0
0
0
0
0
% R
% Ser:
0
8
8
8
15
8
15
58
0
15
22
8
8
43
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
36
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _