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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MXI1
All Species:
31.79
Human Site:
S225
Identified Species:
77.71
UniProt:
P50539
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50539
NP_001008541.1
228
26062
S225
S
S
A
S
V
K
L
S
F
T
S
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001142168
296
32564
S293
S
S
A
S
V
K
L
S
F
T
S
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001085389
228
26072
S225
S
S
A
S
V
K
L
S
F
T
S
_
_
_
_
Dog
Lupus familis
XP_852395
291
32501
S288
S
S
A
S
V
K
L
S
F
T
S
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P50540
228
25959
S225
S
S
A
S
V
K
L
S
F
A
S
_
_
_
_
Rat
Rattus norvegicus
O09015
228
26003
S225
S
S
A
S
V
K
L
S
F
T
S
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512779
249
28127
S246
S
S
A
S
V
K
L
S
F
A
S
_
_
_
_
Chicken
Gallus gallus
NP_001012929
264
29401
S261
S
S
A
S
V
K
L
S
F
A
S
_
_
_
_
Frog
Xenopus laevis
Q0VH34
221
25215
S209
Y
S
S
S
G
L
K
S
I
G
L
Q
N
N
P
Zebra Danio
Brachydanio rerio
P50541
243
27624
A240
S
S
C
S
I
K
L
A
F
S
S
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.2
99.5
73.8
N.A.
96
98.2
N.A.
81.9
75.3
57
55.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
70.6
100
76.9
N.A.
98.2
98.6
N.A.
87.9
79.9
74.1
67.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
90.9
100
N.A.
90.9
90.9
20
63.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
90.9
100
N.A.
90.9
90.9
26.6
90.9
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
80
0
0
0
0
10
0
30
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
90
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
90
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
90
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
90
100
10
100
0
0
0
90
0
10
90
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% T
% Val:
0
0
0
0
80
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
90
90
90
90
% _