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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX5
All Species:
12.12
Human Site:
S268
Identified Species:
33.33
UniProt:
P50542
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50542
NP_000310.2
639
70865
S268
F
T
R
P
V
N
T
S
A
L
D
M
E
F
E
Chimpanzee
Pan troglodytes
XP_001164247
639
70836
S268
F
T
R
P
V
N
T
S
A
L
D
M
E
F
E
Rhesus Macaque
Macaca mulatta
XP_001112429
639
70866
S268
F
T
R
P
V
N
T
S
A
L
D
M
E
F
E
Dog
Lupus familis
XP_543837
640
70995
A269
F
T
R
P
V
N
T
A
A
L
D
M
E
F
E
Cat
Felis silvestris
Mouse
Mus musculus
O09012
639
70737
A270
T
R
P
G
N
K
I
A
A
L
Q
V
E
F
E
Rat
Rattus norvegicus
Q925N3
602
66853
M259
D
T
E
F
W
D
K
M
Q
A
E
W
E
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMQ9
645
71772
S273
F
A
R
S
G
N
L
S
A
L
D
T
E
F
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397319
525
60252
L215
D
K
I
S
S
E
E
L
S
S
K
H
P
W
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35056
612
69306
E275
A
E
E
V
L
P
S
E
L
V
N
D
D
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
97.6
N.A.
93.7
39.7
N.A.
N.A.
78.9
N.A.
N.A.
N.A.
N.A.
41.1
N.A.
N.A.
Protein Similarity:
100
99.8
99.6
98.5
N.A.
96.5
56.8
N.A.
N.A.
87.7
N.A.
N.A.
N.A.
N.A.
56.3
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
33.3
13.3
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
46.6
26.6
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
0
0
23
67
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
0
0
0
0
12
0
0
0
0
56
12
12
0
0
% D
% Glu:
0
12
23
0
0
12
12
12
0
0
12
0
78
12
67
% E
% Phe:
56
0
0
12
0
0
0
0
0
0
0
0
0
67
0
% F
% Gly:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
12
12
0
0
0
12
0
0
0
0
% K
% Leu:
0
0
0
0
12
0
12
12
12
67
0
0
0
12
12
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
45
0
0
12
% M
% Asn:
0
0
0
0
12
56
0
0
0
0
12
0
0
0
12
% N
% Pro:
0
0
12
45
0
12
0
0
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% Q
% Arg:
0
12
56
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
23
12
0
12
45
12
12
0
0
0
0
0
% S
% Thr:
12
56
0
0
0
0
45
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
12
45
0
0
0
0
12
0
12
0
0
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
12
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _