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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX5
All Species:
16.36
Human Site:
T630
Identified Species:
45
UniProt:
P50542
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50542
NP_000310.2
639
70865
T630
A
D
A
R
D
L
S
T
L
L
T
M
F
G
L
Chimpanzee
Pan troglodytes
XP_001164247
639
70836
T630
A
D
A
R
D
L
S
T
L
L
T
M
F
G
L
Rhesus Macaque
Macaca mulatta
XP_001112429
639
70866
T630
A
D
A
R
D
L
S
T
L
L
T
M
F
G
L
Dog
Lupus familis
XP_543837
640
70995
T631
A
D
A
R
D
L
P
T
L
L
A
M
F
G
L
Cat
Felis silvestris
Mouse
Mus musculus
O09012
639
70737
A630
A
D
A
R
D
L
S
A
L
L
A
M
F
G
L
Rat
Rattus norvegicus
Q925N3
602
66853
V593
A
N
L
G
D
L
D
V
L
L
R
A
F
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMQ9
645
71772
T636
A
D
A
H
D
L
P
T
L
L
Q
A
F
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397319
525
60252
R517
I
E
N
R
D
L
T
R
L
N
K
E
F
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35056
612
69306
G600
L
L
Q
E
V
K
P
G
M
D
L
K
R
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
97.6
N.A.
93.7
39.7
N.A.
N.A.
78.9
N.A.
N.A.
N.A.
N.A.
41.1
N.A.
N.A.
Protein Similarity:
100
99.8
99.6
98.5
N.A.
96.5
56.8
N.A.
N.A.
87.7
N.A.
N.A.
N.A.
N.A.
56.3
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
46.6
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
53.3
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
78
0
67
0
0
0
0
12
0
0
23
23
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
0
89
0
12
0
0
12
0
0
0
0
0
% D
% Glu:
0
12
0
12
0
0
0
0
0
0
0
12
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
89
12
0
% F
% Gly:
0
0
0
12
0
0
0
12
0
0
0
0
0
67
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
0
0
0
12
0
0
0
0
12
12
0
0
12
% K
% Leu:
12
12
12
0
0
89
0
0
89
78
12
0
0
0
78
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
56
0
0
0
% M
% Asn:
0
12
12
0
0
0
0
0
0
12
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
67
0
0
0
12
0
0
12
0
12
0
0
% R
% Ser:
0
0
0
0
0
0
45
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
12
56
0
0
34
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _