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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX5
All Species:
22.12
Human Site:
Y522
Identified Species:
60.83
UniProt:
P50542
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50542
NP_000310.2
639
70865
Y522
L
S
V
R
P
N
D
Y
L
L
W
N
K
L
G
Chimpanzee
Pan troglodytes
XP_001164247
639
70836
Y522
L
S
V
R
P
N
D
Y
L
L
W
N
K
L
G
Rhesus Macaque
Macaca mulatta
XP_001112429
639
70866
Y522
L
S
V
R
P
N
D
Y
L
L
W
N
K
L
G
Dog
Lupus familis
XP_543837
640
70995
Y523
L
S
V
R
P
N
D
Y
L
L
W
N
K
L
G
Cat
Felis silvestris
Mouse
Mus musculus
O09012
639
70737
Y522
L
S
V
R
P
N
D
Y
L
M
W
N
K
L
G
Rat
Rattus norvegicus
Q925N3
602
66853
Y484
L
T
V
R
P
E
D
Y
S
L
W
N
R
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMQ9
645
71772
H528
L
S
V
R
P
N
D
H
L
L
W
N
K
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397319
525
60252
N418
R
L
G
A
T
L
A
N
G
Q
K
S
E
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35056
612
69306
E491
L
R
V
N
P
N
D
E
L
M
W
N
R
L
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
97.6
N.A.
93.7
39.7
N.A.
N.A.
78.9
N.A.
N.A.
N.A.
N.A.
41.1
N.A.
N.A.
Protein Similarity:
100
99.8
99.6
98.5
N.A.
96.5
56.8
N.A.
N.A.
87.7
N.A.
N.A.
N.A.
N.A.
56.3
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
73.3
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
89
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
12
0
0
0
0
12
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
89
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
0
67
0
0
% K
% Leu:
89
12
0
0
0
12
0
0
78
67
0
0
0
89
0
% L
% Met:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
78
0
12
0
0
0
89
0
0
0
% N
% Pro:
0
0
0
0
89
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Q
% Arg:
12
12
0
78
0
0
0
0
0
0
0
0
23
0
0
% R
% Ser:
0
67
0
0
0
0
0
0
12
0
0
12
0
0
0
% S
% Thr:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
89
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
89
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _