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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VASP
All Species:
12.73
Human Site:
S289
Identified Species:
35
UniProt:
P50552
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50552
NP_003361.1
380
39830
S289
E
K
T
P
K
D
E
S
A
N
Q
E
E
P
E
Chimpanzee
Pan troglodytes
XP_524304
380
39930
S289
E
K
T
P
K
D
E
S
A
N
Q
E
E
P
E
Rhesus Macaque
Macaca mulatta
XP_001106536
421
44068
S330
E
K
T
P
K
D
E
S
A
N
Q
E
E
P
E
Dog
Lupus familis
XP_537553
419
44781
P308
A
E
E
P
S
T
S
P
S
P
G
T
R
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P70460
375
39648
E284
G
E
K
P
P
K
D
E
S
A
S
E
E
S
E
Rat
Rattus norvegicus
O08719
393
42076
P303
T
E
D
P
S
T
S
P
S
P
G
S
R
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006487
418
44712
S331
G
K
K
P
W
E
R
S
N
S
V
E
K
P
V
Frog
Xenopus laevis
Q64GL0
692
73902
S602
Q
N
E
D
A
S
L
S
S
S
P
V
T
R
G
Zebra Danio
Brachydanio rerio
NP_991196
376
40801
D296
K
D
E
S
Q
N
D
D
L
N
R
G
Q
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
88.3
45.3
N.A.
87.8
47.3
N.A.
N.A.
46.8
30.7
49.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
88.8
58.7
N.A.
90.7
60.8
N.A.
N.A.
59.8
38.8
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
26.6
6.6
N.A.
N.A.
33.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
46.6
20
N.A.
N.A.
53.3
26.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
0
34
12
0
0
0
23
23
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
12
0
34
23
12
0
0
0
0
0
0
0
% D
% Glu:
34
34
34
0
0
12
34
12
0
0
0
56
45
0
45
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
23
0
0
0
0
0
0
0
0
0
23
12
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
45
23
0
34
12
0
0
0
0
0
0
12
0
0
% K
% Leu:
0
0
0
0
0
0
12
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
12
0
0
12
45
0
0
0
12
0
% N
% Pro:
0
0
0
78
12
0
0
23
0
23
12
0
0
45
0
% P
% Gln:
12
0
0
0
12
0
0
0
0
0
34
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
12
0
23
12
0
% R
% Ser:
0
0
0
12
23
12
23
56
45
23
12
12
0
12
0
% S
% Thr:
12
0
34
0
0
23
0
0
0
0
0
12
12
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
12
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _