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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM2
All Species:
18.18
Human Site:
T504
Identified Species:
44.44
UniProt:
P50570
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50570
NP_001005360.1
870
98064
T504
A
N
A
Q
Q
R
S
T
Q
L
N
K
K
R
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103119
870
98099
T504
A
N
A
Q
Q
R
S
T
Q
L
N
K
K
R
A
Dog
Lupus familis
XP_542065
865
97464
T504
A
N
A
Q
Q
R
S
T
Q
L
N
K
K
R
A
Cat
Felis silvestris
Mouse
Mus musculus
P39054
870
98127
T504
A
N
A
Q
Q
R
S
T
Q
L
N
K
K
R
A
Rat
Rattus norvegicus
P39052
870
98212
T504
A
N
A
Q
Q
R
S
T
Q
L
N
K
K
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
I336
S
A
T
L
L
Q
L
I
T
K
F
A
T
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
E500
A
N
A
Q
N
K
S
E
N
A
N
K
T
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P39055
830
93389
E471
V
S
H
M
R
E
R
E
Q
I
A
K
Q
Q
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
V427
S
A
L
F
V
P
D
V
P
F
E
V
L
V
R
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
I404
G
G
A
R
I
Y
Y
I
Y
N
N
V
F
G
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
95.1
N.A.
98.1
98
N.A.
N.A.
N.A.
N.A.
32.9
N.A.
64.4
N.A.
61.9
N.A.
Protein Similarity:
100
N.A.
100
97.2
N.A.
99
99.1
N.A.
N.A.
N.A.
N.A.
51
N.A.
76.9
N.A.
76.5
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
0
N.A.
46.6
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
53.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.5
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
20
70
0
0
0
0
0
0
10
10
10
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
20
0
0
10
0
0
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
10
0
10
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
0
20
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
20
0
10
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
10
0
0
0
10
0
70
50
0
0
% K
% Leu:
0
0
10
10
10
0
10
0
0
50
0
0
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
60
0
0
10
0
0
0
10
10
70
0
0
0
10
% N
% Pro:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
60
50
10
0
0
60
0
0
0
10
10
0
% Q
% Arg:
0
0
0
10
10
50
10
0
0
0
0
0
0
50
10
% R
% Ser:
20
10
0
0
0
0
60
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
50
10
0
0
0
20
0
10
% T
% Val:
10
0
0
0
10
0
0
10
0
0
0
20
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _