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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFSF10
All Species:
13.33
Human Site:
S225
Identified Species:
32.59
UniProt:
P50591
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50591
NP_003801.1
281
32509
S225
D
P
I
L
L
M
K
S
A
R
N
S
C
W
S
Chimpanzee
Pan troglodytes
XP_516879
281
32443
S225
D
P
I
L
L
M
K
S
A
R
N
S
C
W
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851765
315
35047
G256
S
S
H
T
L
M
K
G
G
S
T
K
Y
W
S
Cat
Felis silvestris
Mouse
Mus musculus
P50592
291
33459
S235
D
P
I
V
L
M
K
S
A
R
N
S
C
W
S
Rat
Rattus norvegicus
Q9ESE2
318
35352
G259
S
S
H
N
L
M
K
G
G
S
T
K
N
W
S
Wallaby
Macropus eugenll
Q9XT48
201
21518
A147
V
H
V
P
L
L
S
A
Q
K
S
V
C
S
G
Platypus
Ornith. anatinus
XP_001506414
302
34659
S246
E
P
I
L
L
L
K
S
A
R
T
S
C
W
S
Chicken
Gallus gallus
Q9I8D8
272
30814
K217
E
E
D
R
L
L
M
K
G
L
D
T
H
S
T
Frog
Xenopus laevis
NP_001163915
280
32022
N224
E
P
L
L
L
M
K
N
V
K
T
M
C
W
S
Zebra Danio
Brachydanio rerio
NP_001002593
299
33508
N243
V
P
I
L
L
M
K
N
A
R
T
T
C
W
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
22.5
N.A.
62.5
24.2
23.4
59.2
23.4
47.6
42.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
40.3
N.A.
74.9
42.1
38.7
74.1
44.8
66.1
62.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
33.3
N.A.
93.3
33.3
13.3
80
6.6
53.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
33.3
N.A.
100
33.3
46.6
93.3
40
80
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
50
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% C
% Asp:
30
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
30
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
20
30
0
0
0
0
0
10
% G
% His:
0
10
20
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
80
10
0
20
0
20
0
0
0
% K
% Leu:
0
0
10
50
100
30
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
70
10
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
20
0
0
30
0
10
0
0
% N
% Pro:
0
60
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
50
0
0
0
0
0
% R
% Ser:
20
20
0
0
0
0
10
40
0
20
10
40
0
20
80
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
50
20
0
0
10
% T
% Val:
20
0
10
10
0
0
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _